{"id":"W3163192401","doi":"10.3390/cells10051262","title":"A Potential Role for HUWE1 in Modulating Cisplatin Sensitivity","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cisplatin; Sensitivity (control systems); Neuroscience; Medicine; Biology; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003475128,0.0002841695,0.0007549043,0.00005294755,0.00003440499,0.00002808607,0.000113576,0.0004883555,0.00001314581],"category_scores_gemma":[0.00007506555,0.0002892877,0.0005030573,0.00009025451,0.00001693871,0.000001493044,0.0001858527,0.0001487355,0.00001228867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002926873,"about_ca_system_score_gemma":0.000170859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001106419,"about_ca_topic_score_gemma":0.00001979401,"domain_scores_codex":[0.9984925,0.0001831426,0.0003502305,0.0005860638,0.00009087124,0.0002971493],"domain_scores_gemma":[0.9992701,0.00003542596,0.0001743637,0.0004159599,0.00004870887,0.00005548395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005965675,0.00006253266,4.502663e-7,0.002965037,0.00009015646,0.00005410842,0.00001301722,0.00008388825,0.1702258,0.00002753219,0.0003467944,0.8261248],"study_design_scores_gemma":[0.0002717721,0.00007611234,3.765847e-7,0.001950838,0.0001928962,0.00005375992,0.00002127953,0.0006965571,0.05778988,0.00004895955,0.938416,0.0004815706],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007703304,0.9948087,0.002950209,0.000002304689,0.0003359782,0.0007121321,0.0001077246,0.00001196262,0.0003006315],"genre_scores_gemma":[0.0008340923,0.9898939,0.005625015,0.00003309671,0.0004742059,0.0001150444,0.001109204,0.00009181954,0.001823623],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9380692,"threshold_uncertainty_score":0.999956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01607682450047402,"score_gpt":0.2869088098169317,"score_spread":0.2708319853164576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}