{"id":"W3163321807","doi":"10.1038/s41698-021-00182-3","title":"A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival","year":2021,"lang":"en","type":"article","venue":"npj Precision Oncology","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Key Research and Development Program of China; National Cancer Institute; National Institutes of Health; Nanjing Medical University; China Postdoctoral Science Foundation; Jiangsu Planned Projects for Postdoctoral Research Funds; Priority Academic Program Development of Jiangsu Higher Education Institutions; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China; Foundation for the National Institutes of Health","keywords":"Single-nucleotide polymorphism; Expression quantitative trait loci; Genome-wide association study; SNP; Oncology; Biology; Genetic association; Survival analysis; Bioinformatics; Medicine; Internal medicine; Computational biology; Genetics; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008047432,0.0004974247,0.0005383,0.0007329848,0.0004965095,0.0006577621,0.0003198717,0.000431411,0.002068334],"category_scores_gemma":[0.001507038,0.0002031471,0.001388735,0.001129849,0.0002627646,0.0002215006,0.0006619699,0.0005106661,0.0001896758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002323204,"about_ca_system_score_gemma":0.0002784289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00208634,"about_ca_topic_score_gemma":0.002292853,"domain_scores_codex":[0.999587,0.0001306049,0.0000439103,0.0001391497,0.00005235485,0.00004710043],"domain_scores_gemma":[0.9990693,0.0003575624,0.0002651971,0.0001192848,0.0000672742,0.0001213362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001368676,0.00006948275,0.9644012,0.0001040588,0.00182058,0.0003850031,0.00009941608,0.0008728018,0.02484461,0.0001540092,0.0003913242,0.005488744],"study_design_scores_gemma":[0.00004148993,0.0001338443,0.9931217,0.00001783294,0.0007376801,0.0003804167,0.000105334,0.003093992,0.001530165,0.0003594052,0.0004670726,0.00001104095],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969162,0.0004225302,0.0009320204,0.0001361356,0.0000124018,0.000006379175,0.001418371,0.0000141348,0.0001417541],"genre_scores_gemma":[0.9979684,0.0001322093,0.0005818658,0.00005793969,0.00001061857,0.00001103134,0.001083677,0.000006654533,0.0001476062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00208634,"threshold_uncertainty_score":0.006919265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03985170307920977,"score_gpt":0.3618009019195455,"score_spread":0.3219491988403357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}