{"id":"W3163452526","doi":"10.3390/biology10050433","title":"An “Omic” Overview of Fragile X Syndrome","year":2021,"lang":"en","type":"review","venue":"Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Université de Sherbrooke","funders":"","keywords":"Fragile X syndrome; FMR1; Biology; Fragile x; Gene silencing; Neuroscience; Phenotype; Regulator; Bioinformatics; Computational biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004719442,0.001078936,0.001056891,0.003217934,0.0002940948,0.0008651822,0.0008439798,0.0009788166,0.006999625],"category_scores_gemma":[0.0007346089,0.0002375927,0.0006079035,0.002163101,0.000465233,0.001388111,0.000796522,0.001815785,0.003240671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007526578,"about_ca_system_score_gemma":0.001112626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001016122,"about_ca_topic_score_gemma":0.001672486,"domain_scores_codex":[0.9998121,0.0000379378,0.00003034355,0.00003394507,0.00006712758,0.00001860505],"domain_scores_gemma":[0.9997252,0.0001302329,0.0000325395,0.000008921325,0.00006982847,0.00003326509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009811587,0.00004799411,0.0002033101,0.01677107,0.0001044045,0.00051254,0.00007195411,0.0002781338,0.001970337,0.006273963,0.08217245,0.8914957],"study_design_scores_gemma":[0.000006931474,0.00004517282,0.000455119,0.002739901,0.0000540319,0.001504008,0.00002901647,0.00003325562,0.0001583047,0.001348224,0.9936169,0.000009164251],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001202899,0.9947299,0.0002926025,0.0008835458,0.0009194312,0.000008991532,0.00006284389,0.00002251555,0.002959813],"genre_scores_gemma":[0.0005740746,0.9963791,0.0004109234,0.0006258554,0.0005710992,0.000009944485,0.0001127186,0.000003965837,0.001312312],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006999625,"threshold_uncertainty_score":0.02341604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05853774593256662,"score_gpt":0.3578456953029588,"score_spread":0.2993079493703922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}