{"id":"W3163619921","doi":"10.1186/s12610-021-00130-y","title":"LRWD1 expression is regulated through DNA methylation in human testicular embryonal carcinoma cells","year":2021,"lang":"en","type":"article","venue":"Basic and Clinical Andrology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cheng Kung University; Ministry of Science and Technology, Taiwan; Academia Sinica","keywords":"DNA methylation; Biology; Methylation; Molecular biology; CpG site; Promoter; Regulation of gene expression; Epigenetics; Gene expression; Methyltransferase; Gene; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003401364,0.0001374472,0.000251443,0.00002367196,0.00007992495,0.0000138499,0.00007168367,0.000419251,0.00006809511],"category_scores_gemma":[0.0001282551,0.000127617,0.0000974472,0.0000894905,0.0001367413,0.000005235599,0.0001182694,0.0001571547,0.000004936551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000532106,"about_ca_system_score_gemma":0.00005771866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000198671,"about_ca_topic_score_gemma":0.0000377262,"domain_scores_codex":[0.99843,0.0002812888,0.0004658978,0.0005229781,0.0000918872,0.0002079849],"domain_scores_gemma":[0.9993802,0.00008056145,0.0001077509,0.0002653614,0.00008824954,0.00007783798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007269411,0.0003988974,0.05572177,0.00001402788,0.00002382151,0.0000354642,0.00004837586,0.00001577614,0.9402981,0.0001689993,0.0003237814,0.002878223],"study_design_scores_gemma":[0.003102794,0.0005398256,0.1573245,0.00001595711,0.00003946097,0.00001203727,0.00003211249,0.0002349792,0.8228798,0.004593382,0.01100804,0.0002171264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994645,0.002935006,0.001145883,0.0003445775,0.0001658676,0.00009577692,0.00000934847,0.000006756773,0.0006517677],"genre_scores_gemma":[0.9971627,0.0006629244,0.000794932,0.0005277687,0.0001965101,0.000006593015,0.0001452067,0.00001348516,0.0004898913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1174184,"threshold_uncertainty_score":0.5204069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02666997460199266,"score_gpt":0.321790850767311,"score_spread":0.2951208761653183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}