{"id":"W3163993890","doi":"10.1136/annrheumdis-2021-eular.3582","title":"POS1375 THE EFFECT OF M694V HOMOZYGOSITY ON THE CAROTID INTIMA-MEDIA THICKNESS AND FLOW MEDIATED DILATATION IN PATIENTS WITH FMF RELATED AMYLOIDOSIS","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; MEFV; Internal medicine; Amyloidosis; Endothelial dysfunction; Familial Mediterranean fever; Intima-media thickness; Gastroenterology; Diabetes mellitus; Risk factor; Cardiology; Pathology; Disease; Gene mutation; Endocrinology; Mutation; Carotid arteries","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004922863,0.000196662,0.0003681842,0.00005967848,0.0001603904,0.00001418369,0.0003694145,0.0001150106,0.0001241374],"category_scores_gemma":[0.001965145,0.00008844626,0.0001264897,0.0003852127,0.000526959,0.00006841117,0.0001788379,0.000192735,0.00001166143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001154701,"about_ca_system_score_gemma":0.00006388936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005199523,"about_ca_topic_score_gemma":0.00002464493,"domain_scores_codex":[0.9976643,0.001382477,0.0003678478,0.0002209759,0.0001553246,0.0002091239],"domain_scores_gemma":[0.9965675,0.002337108,0.0003084723,0.0006076753,0.0001509774,0.00002826592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005405553,0.002083403,0.9429557,0.001252863,0.003677564,0.000007018622,0.006217583,0.0002478762,0.004677244,0.001462658,0.0050786,0.02693395],"study_design_scores_gemma":[0.001888822,0.0002808296,0.9612077,0.0009187509,0.0002718891,0.000002658546,0.0003361221,0.00005754081,0.03397499,0.0009229118,0.000006131088,0.0001316022],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960659,0.001464592,0.000004515795,0.001196356,0.0002509895,0.0006165524,0.0003360268,0.00001701741,0.00004801198],"genre_scores_gemma":[0.9994215,0.0001238474,0.00000805121,0.0001747991,0.000002171376,0.00004531186,0.0001866278,0.00001504798,0.00002267508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02929775,"threshold_uncertainty_score":0.3606734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007041725432700012,"score_gpt":0.2075395184925437,"score_spread":0.2004977930598437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}