{"id":"W3163993890","doi":"10.1136/annrheumdis-2021-eular.3582","title":"POS1375 THE EFFECT OF M694V HOMOZYGOSITY ON THE CAROTID INTIMA-MEDIA THICKNESS AND FLOW MEDIATED DILATATION IN PATIENTS WITH FMF RELATED AMYLOIDOSIS","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; MEFV; Internal medicine; Amyloidosis; Endothelial dysfunction; Familial Mediterranean fever; Intima-media thickness; Gastroenterology; Diabetes mellitus; Risk factor; Cardiology; Pathology; Disease; Gene mutation; Endocrinology; Mutation; Carotid arteries","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003530176,0.0008504551,0.0006394522,0.0005989236,0.0005111841,0.0006141549,0.0003678632,0.001333662,0.007025926],"category_scores_gemma":[0.001578451,0.0002684706,0.0007163563,0.0004814083,0.0004087123,0.0003827362,0.0002751684,0.0007048838,0.000721305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001810514,"about_ca_system_score_gemma":0.0001810321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001079121,"about_ca_topic_score_gemma":0.0006477587,"domain_scores_codex":[0.9995189,0.0001708002,0.00005402154,0.0001198245,0.00005564045,0.00008093206],"domain_scores_gemma":[0.9991725,0.0003409379,0.0001580922,0.00004831884,0.00004821095,0.0002318541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03188518,0.001154226,0.8481295,0.0001581981,0.00126924,0.02136365,0.0005415654,0.0004918132,0.07556019,0.0005894642,0.0008689135,0.01798814],"study_design_scores_gemma":[0.0003479528,0.003300369,0.9783799,0.00004015231,0.0006076714,0.01206123,0.0003442481,0.00108114,0.002306096,0.000582958,0.0008977556,0.00005051034],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982752,0.0002398383,0.0001430167,0.0001011934,0.00004889516,0.00000477465,0.0001814132,0.000009203061,0.0009965149],"genre_scores_gemma":[0.9993396,0.00003488594,0.00006315704,0.00004416465,0.00004003674,0.000002985636,0.00009226404,0.000005279532,0.0003775072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007025926,"threshold_uncertainty_score":0.02350408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007041725432700012,"score_gpt":0.2075395184925437,"score_spread":0.2004977930598437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}