{"id":"W3164071506","doi":"10.3168/jds.2020-20034","title":"Selenomethionine activates selenoprotein S, suppresses Fas/FasL and the mitochondrial pathway, and reduces Escherichia coli-induced apoptosis of bovine mammary epithelial cells","year":2021,"lang":"en","type":"article","venue":"Journal of Dairy Science","topic":"Selenium in Biological Systems","field":"Nursing","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Fas ligand; Apoptosis; Cytochrome c; Biology; Molecular biology; Mitochondrion; Programmed cell death; Caspase; FADD; Caspase 8; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001729137,0.0002575498,0.0003701621,0.0002338244,0.0001194546,0.0001905321,0.0001630634,0.0002547347,0.000660186],"category_scores_gemma":[0.0001375251,0.0001054752,0.0002660826,0.0001561312,0.0001416855,0.0001670586,0.0001910941,0.0004487949,0.0001885438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001988558,"about_ca_system_score_gemma":0.0002516917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008202682,"about_ca_topic_score_gemma":0.001332204,"domain_scores_codex":[0.9998549,0.00003077102,0.00002161871,0.00001900128,0.00003748082,0.00003625287],"domain_scores_gemma":[0.9999305,0.000007731016,0.00001851817,0.000008065447,0.00001787122,0.00001739018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004482506,0.00006494469,0.0002386521,0.00005398675,0.000007325757,0.00003673244,0.00001728376,0.00002216072,0.9975986,0.00002239681,0.0000365186,0.001453128],"study_design_scores_gemma":[0.00007784214,0.001222485,0.005769118,0.00001220654,0.00002283351,0.0001653305,0.0000654114,0.0004546597,0.9893524,0.00003057368,0.00282267,0.000004475812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946151,0.003306977,0.0009601415,0.000109454,0.00003191288,0.00002103369,0.0001503883,0.00004410644,0.0007608263],"genre_scores_gemma":[0.994754,0.001195436,0.001149611,0.00007943971,0.00001025118,0.00002654958,0.0004606855,0.000008320294,0.002315771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008202682,"threshold_uncertainty_score":0.002208531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698912331215247,"score_gpt":0.2487676436763025,"score_spread":0.23177852036415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}