{"id":"W3164229011","doi":"10.82308/22155","title":"The role of mTORC1/4EBP1 signaling pathway in regulation of orexin ligand-receptor system and sleep-wake states","year":2017,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University","keywords":"mTORC1; Orexin; Chemistry; Signal transduction; Cell biology; Receptor; Biology; Biochemistry; PI3K/AKT/mTOR pathway; Neuropeptide","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001803524,0.0003389276,0.0003323187,0.0005294989,0.0002542664,0.0005216656,0.0002464795,0.0003413621,0.002547748],"category_scores_gemma":[0.0001524316,0.0001557113,0.0003218603,0.0003165549,0.0003262659,0.0003035019,0.000454054,0.000570344,0.0003659378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004581229,"about_ca_system_score_gemma":0.000407098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008622956,"about_ca_topic_score_gemma":0.0007336535,"domain_scores_codex":[0.9998852,0.00001818562,0.000008138544,0.00002604851,0.0000232123,0.00003915759],"domain_scores_gemma":[0.9999281,0.000009346339,0.00002772791,0.000003100361,0.00001320497,0.00001839458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004490298,0.0005408949,0.02341554,0.004117932,0.0005007343,0.004133394,0.0006005598,0.004401986,0.7875543,0.01316738,0.01058241,0.1464946],"study_design_scores_gemma":[0.0003503391,0.002103532,0.5747962,0.000667966,0.0005460768,0.005214586,0.001476453,0.01174609,0.2536978,0.017683,0.1314907,0.0002272955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6359111,0.3265224,0.01192973,0.002687978,0.0007350394,0.0001164916,0.001942319,0.0005382399,0.01961669],"genre_scores_gemma":[0.9316049,0.05617757,0.002612685,0.0005178566,0.0001765877,0.00009985617,0.0009644408,0.00004370709,0.007802463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002547748,"threshold_uncertainty_score":0.008523047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02331975975096415,"score_gpt":0.249635056443408,"score_spread":0.2263152966924438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}