{"id":"W3164256537","doi":"10.1038/s41598-021-91276-2","title":"High-resolution metabolomic biomarkers for lung cancer diagnosis and prognosis","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Mitacs","keywords":"Lung cancer; Metabolomics; Palmitic acid; Medicine; Cancer; Internal medicine; Oncology; Bioinformatics; Biology; Biochemistry; Fatty acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005460305,0.0001338704,0.0001966646,0.0000692197,0.0003056115,0.0001264321,0.000055753,0.0000771075,0.00004477769],"category_scores_gemma":[0.000282223,0.0001230134,0.0001057924,0.0002319149,0.0001492546,0.000006517359,0.0001389511,0.0000324576,2.980574e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001675047,"about_ca_system_score_gemma":0.000125674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003973464,"about_ca_topic_score_gemma":0.0001234576,"domain_scores_codex":[0.9984904,0.00003100987,0.000268456,0.000795379,0.0001415537,0.0002732376],"domain_scores_gemma":[0.9991546,0.00001430736,0.0001547544,0.0003658462,0.000233172,0.00007731969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003002775,0.00008956147,0.0502869,0.00007853583,0.0004665218,0.00002398038,0.00002736917,0.00002235927,0.8461056,0.0004715506,0.09827533,0.004122275],"study_design_scores_gemma":[0.000255712,0.00003183771,0.006062984,0.00001471654,0.0001656365,0.00003480681,0.000042649,0.0001125719,0.7925227,0.0008565618,0.1996979,0.0002019049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9607009,0.03274914,0.001118424,0.0006568027,0.004241105,0.0003913509,0.00005139916,0.00001325496,0.00007767187],"genre_scores_gemma":[0.9866707,0.002765966,0.00744911,0.00007484943,0.0002042049,0.0009826362,0.0002828682,0.00002016591,0.001549457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1014226,"threshold_uncertainty_score":0.501634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225077740027639,"score_gpt":0.2707992847114876,"score_spread":0.2585485073112113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}