{"id":"W3164273949","doi":"10.1136/annrheumdis-2021-eular.167","title":"POS1024 GUSELKUMAB PROVIDES SUSTAINED DOMAIN-SPECIFIC AND COMPREHENSIVE EFFICACY AS ASSESSED USING COMPOSITE ENDPOINTS IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Sanofi Genzyme; University of Glasgow; Celgene; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Psoriatic arthritis; Internal medicine; Clinical endpoint; Placebo; Randomized controlled trial; Gastroenterology; Surgery; Arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004642597,0.0004074787,0.001077838,0.0001898135,0.0001622985,0.0005144174,0.0002443057,0.0004336131,0.004243841],"category_scores_gemma":[0.0004619679,0.0001586692,0.0004639317,0.0002299888,0.0002383573,0.000485028,0.0001960963,0.00133112,0.001283214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191167,"about_ca_system_score_gemma":0.0003453919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002516382,"about_ca_topic_score_gemma":0.0006261903,"domain_scores_codex":[0.9998056,0.00006138781,0.00001393671,0.00002310841,0.00003016786,0.0000657483],"domain_scores_gemma":[0.9998357,0.00003440851,0.00003383911,0.00001563345,0.00001074568,0.00006964165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2083271,0.01245808,0.01174446,0.001396849,0.001459747,0.0007835547,0.0001673604,0.001967085,0.1883238,0.0007409719,0.007900705,0.5647303],"study_design_scores_gemma":[0.1791922,0.4235185,0.2935088,0.0003595395,0.002507154,0.005176534,0.000452897,0.01187098,0.05718653,0.002087232,0.02392927,0.0002103358],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906572,0.003627852,0.0004483737,0.0004212925,0.0001127394,0.00008169729,0.0004077828,0.0002262409,0.004016671],"genre_scores_gemma":[0.9967178,0.0007854908,0.0003506569,0.0003096373,0.00005279753,0.00004409624,0.0004630479,0.00001635613,0.00126023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004243841,"threshold_uncertainty_score":0.01419711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02280936025382823,"score_gpt":0.2926631260409889,"score_spread":0.2698537657871607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}