{"id":"W3164323000","doi":"10.1093/biolre/ioab107","title":"Dynamics of small non-coding RNAs in bovine scNT embryos through the maternal-to-embryonic transition","year":2021,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre","funders":"National Institute of Food and Agriculture; Utah Agricultural Experiment Station; U.S. Department of Agriculture","keywords":"Biology; Somatic cell nuclear transfer; Blastocyst; Genetics; Reprogramming; Embryo; Epigenetics; microRNA; Embryonic stem cell; Inner cell mass; Embryogenesis; Piwi-interacting RNA; Transcriptome; Andrology; Cell biology; RNA; Cell; Gene expression; Gene; RNA interference","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002606866,0.00009532136,0.0001535116,0.00004395437,0.00002988229,0.000003550688,0.0001017888,0.0001276163,0.00001027048],"category_scores_gemma":[0.0001058652,0.00008322651,0.00007335374,0.0001687849,0.00009303178,0.000004565395,0.00005146673,0.00005907813,0.000001910797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003219798,"about_ca_system_score_gemma":0.00006927047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001005036,"about_ca_topic_score_gemma":0.0001571292,"domain_scores_codex":[0.9990422,0.0001050008,0.000272497,0.0004011481,0.00004979342,0.0001293552],"domain_scores_gemma":[0.9991975,0.000007046641,0.0001478703,0.0004820226,0.0001481089,0.00001738916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001456071,0.00005700942,0.001620871,0.00006157166,0.00003533084,0.000001019859,0.0001026652,0.0008595373,0.9926564,0.0002630284,0.00005718544,0.004139752],"study_design_scores_gemma":[0.0002861794,0.0001510412,0.0275734,0.00004130786,0.00001929614,0.00003672214,0.0001254942,0.0003102694,0.9696789,0.000401076,0.001288181,0.00008809237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711581,0.00138267,0.02485859,0.002009157,0.0002664512,0.000211576,0.00001994944,0.000005224512,0.00008827263],"genre_scores_gemma":[0.9975232,0.0003123875,0.001526614,0.00003750937,0.0001775735,0.00001344646,0.0002514152,0.00001122065,0.0001465833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02636514,"threshold_uncertainty_score":0.3393878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153326851725294,"score_gpt":0.2505004342580164,"score_spread":0.2389671657407634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}