{"id":"W3164323000","doi":"10.1093/biolre/ioab107","title":"Dynamics of small non-coding RNAs in bovine scNT embryos through the maternal-to-embryonic transition","year":2021,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre","funders":"National Institute of Food and Agriculture; Utah Agricultural Experiment Station; U.S. Department of Agriculture","keywords":"Biology; Somatic cell nuclear transfer; Blastocyst; Genetics; Reprogramming; Embryo; Epigenetics; microRNA; Embryonic stem cell; Inner cell mass; Embryogenesis; Piwi-interacting RNA; Transcriptome; Andrology; Cell biology; RNA; Cell; Gene expression; Gene; RNA interference","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001273228,0.00007651077,0.0001536431,0.0002441467,0.0001517655,0.0003859506,0.00009754075,0.0001655479,0.0005814299],"category_scores_gemma":[0.0002418705,0.00009959128,0.00009387265,0.0001746858,0.0001276348,0.0001324903,0.0001443278,0.0002471897,0.0003647777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002827583,"about_ca_system_score_gemma":0.0001516793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001767209,"about_ca_topic_score_gemma":0.00247215,"domain_scores_codex":[0.9998901,0.00001103347,0.000008629258,0.00003833882,0.00003725019,0.00001466879],"domain_scores_gemma":[0.9998525,0.00003272643,0.00005234484,0.000006760853,0.00003487783,0.00002072891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001233251,0.000006729753,0.005554809,0.00003244115,0.00000680542,0.00009206824,0.0001372671,0.0001221496,0.9888303,0.0001411269,0.00005824825,0.004894777],"study_design_scores_gemma":[0.00001272371,0.0002936164,0.4765832,0.00003978054,0.00005159535,0.0005763328,0.000414705,0.003693051,0.5078033,0.0002773174,0.01022754,0.0000267961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911533,0.002410852,0.003221651,0.00003688849,0.00001170137,0.000008077834,0.0006503033,0.0000439145,0.002463448],"genre_scores_gemma":[0.9937901,0.0009695434,0.001867614,0.00006563478,0.000005589959,0.00002966398,0.001044607,0.00003530757,0.00219209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001767209,"threshold_uncertainty_score":0.003513873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153326851725294,"score_gpt":0.2505004342580164,"score_spread":0.2389671657407634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}