{"id":"W3164440162","doi":"10.1136/annrheumdis-2021-eular.211","title":"POS0901 IXEKIZUMAB SHOWS A DISTINCT PATTERN OF PAIN IMPROVEMENT BEYOND INFLAMMATION IN RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Janssen Research and Development; Janssen Scientific Affairs; McGovern Medical School; University of Pennsylvania","keywords":"Medicine; BASDAI; Ixekizumab; Axial spondyloarthritis; Adalimumab; Placebo; Clinical endpoint; Internal medicine; Randomized controlled trial; Physical therapy; Ankylosing spondylitis; Arthritis; Rheumatoid arthritis; Secukinumab; Pathology; Psoriatic arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004790743,0.0003276911,0.0004686974,0.0002988472,0.0001205624,0.0004232615,0.0002058223,0.0005314838,0.003236841],"category_scores_gemma":[0.0009913708,0.0001183291,0.0003594218,0.0002874018,0.000300236,0.0003452007,0.0001631883,0.0007082233,0.000761225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002034493,"about_ca_system_score_gemma":0.0001711425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004060968,"about_ca_topic_score_gemma":0.0006269944,"domain_scores_codex":[0.9997283,0.00006288776,0.0000272428,0.00004897964,0.00006134297,0.00007116242],"domain_scores_gemma":[0.9994149,0.0001829007,0.0001453973,0.00006701925,0.00008493927,0.0001048629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03106248,0.001792933,0.2499648,0.00100152,0.0005082578,0.006001617,0.0002903171,0.0007318714,0.4529783,0.0007349994,0.0064196,0.2485133],"study_design_scores_gemma":[0.0005869659,0.01700824,0.9432242,0.00005719961,0.0002219095,0.01134887,0.0001966384,0.0006438157,0.02080073,0.0002836628,0.005601261,0.00002643913],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796866,0.004502133,0.0008750482,0.0005456428,0.0001648344,0.00006494491,0.0008225116,0.0001101256,0.0132282],"genre_scores_gemma":[0.9968824,0.000429854,0.0002973828,0.0003327387,0.00005963514,0.00001732097,0.0005575418,0.00001065727,0.00141238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003236841,"threshold_uncertainty_score":0.01082826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01669985454979202,"score_gpt":0.2647788474993066,"score_spread":0.2480789929495146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}