{"id":"W3164467933","doi":"10.1016/j.cjca.2021.05.006","title":"Increased Expression of Proatherogenic Proteins in Immune Cell Subtypes in Tobacco Cigarette Smokers But Not in Electronic Cigarette Vapers","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Clinical and Translational Science Institute, University of California, Los Angeles; National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institute on Aging; Office of the President, University of California; University of California, Los Angeles; National Institutes of Health; Center for AIDS Research, University of Washington; Tobacco-Related Disease Research Program","keywords":"Inflammasome; Medicine; TLR4; Oxidative stress; Immune system; Nicotine; Receptor; Immunology; Signalling; Inflammation; Cell biology; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270768,0.0001304958,0.0002158403,0.0005188588,0.0002157671,0.0003456781,0.00007862571,0.0002878543,0.00251494],"category_scores_gemma":[0.0002132569,0.0001375953,0.0001883605,0.0003206249,0.0001833369,0.0001696704,0.0001484947,0.0003708208,0.0002165515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007834878,"about_ca_system_score_gemma":0.00008147572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000785267,"about_ca_topic_score_gemma":0.001012397,"domain_scores_codex":[0.9998821,0.00001308382,0.000009127862,0.00003762136,0.0000293305,0.00002863317],"domain_scores_gemma":[0.9998716,0.00002234166,0.00003183315,0.00001088185,0.0000280333,0.0000352684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002131548,0.0002009458,0.1758214,0.0001464443,0.0001272614,0.0008071406,0.0005032326,0.00002523887,0.8092183,0.00009757804,0.0001400869,0.0107808],"study_design_scores_gemma":[0.00001544546,0.0003721975,0.9653726,0.00001508909,0.00008676564,0.001040216,0.0004844785,0.0001675927,0.0313565,0.0001288206,0.0009522623,0.000007931881],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979289,0.0009097399,0.0002650556,0.00004246227,0.00002083502,0.000009953105,0.0001351573,0.000005809329,0.000682117],"genre_scores_gemma":[0.9976729,0.0004187133,0.0002170113,0.0000506868,0.00001762886,0.00001715151,0.0001485723,0.000003929828,0.001453459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00251494,"threshold_uncertainty_score":0.008413255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004823243318934098,"score_gpt":0.1928670286173043,"score_spread":0.1880437852983702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}