{"id":"W3164519483","doi":"10.1136/annrheumdis-2021-eular.358","title":"POS0651 CLINICAL AND FUNCTIONAL RESPONSE TO TOFACITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS: PROBABILITY PLOT ANALYSIS OF RESULTS FROM A 48-WEEK PHASE 3b/4 METHOTREXATE WITHDRAWAL STUDY","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Tofacitinib; Medicine; Rheumatoid arthritis; Internal medicine; Methotrexate; Post-hoc analysis; Clinical endpoint; Abatacept; Phases of clinical research; Clinical trial; Rituximab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01597022,0.0007092137,0.002091143,0.0008033189,0.000334365,0.001214193,0.0006694532,0.001167257,0.004679072],"category_scores_gemma":[0.02059519,0.000427301,0.00373659,0.0007751963,0.000751132,0.001391716,0.0005688209,0.002110096,0.0006776329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004674136,"about_ca_system_score_gemma":0.0004549233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004630433,"about_ca_topic_score_gemma":0.0006025956,"domain_scores_codex":[0.9901113,0.007305546,0.0005282846,0.0008604224,0.0008779828,0.0003163983],"domain_scores_gemma":[0.9598945,0.03153317,0.004793701,0.001880571,0.0009601127,0.0009378287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5344645,0.001914577,0.3270316,0.001190682,0.01089393,0.0005712235,0.0003040906,0.01357245,0.01233263,0.000713143,0.003657591,0.09335364],"study_design_scores_gemma":[0.02680129,0.06671801,0.836019,0.000146567,0.006338945,0.001694004,0.0002044135,0.05377674,0.002712495,0.001822839,0.003551591,0.0002140598],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931386,0.001766212,0.001608019,0.0001995151,0.00003549096,0.0001525406,0.001800615,0.00009154735,0.001207532],"genre_scores_gemma":[0.997551,0.0001837091,0.0005388141,0.00009016703,0.00003459451,0.00006302235,0.001134588,0.00002540846,0.0003786146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01597022,"threshold_uncertainty_score":0.0844596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05655714182587063,"score_gpt":0.353556543390873,"score_spread":0.2969994015650024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}