{"id":"W3164572170","doi":"10.3390/toxins13060378","title":"Therapeutic Uses of Bacterial Subunit Toxins","year":2021,"lang":"en","type":"review","venue":"Toxins","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Cholera toxin; Protein subunit; Biology; Shiga toxin; Endoplasmic-reticulum-associated protein degradation; Endoplasmic reticulum; Immunotoxin; Cell biology; Anthrax toxin; Fusion protein; Unfolded protein response; Biochemistry; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002902098,0.0004475605,0.0003944912,0.000530595,0.000292807,0.0006716122,0.0002492565,0.0007777713,0.002422629],"category_scores_gemma":[0.0002315493,0.00009270252,0.0003966459,0.0003276224,0.0004845178,0.0003659736,0.0006866574,0.001249807,0.0007320201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004643786,"about_ca_system_score_gemma":0.0003426256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000362742,"about_ca_topic_score_gemma":0.0004183633,"domain_scores_codex":[0.9997819,0.00005094769,0.00001230264,0.00002885842,0.0000655953,0.00006047258],"domain_scores_gemma":[0.9999273,0.00001485953,0.00001723906,0.00001077119,0.00001244565,0.0000173536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001553712,0.0009755829,0.001507446,0.002310717,0.0001540317,0.001721383,0.0002889183,0.001140145,0.5162591,0.01901032,0.00609435,0.4489843],"study_design_scores_gemma":[0.0005487569,0.0129996,0.008844959,0.00105616,0.0003642529,0.01118595,0.0003622053,0.002536065,0.377785,0.009961439,0.5742881,0.00006744957],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3313648,0.540296,0.03952661,0.00740983,0.002152851,0.0005061546,0.0007531866,0.000809352,0.07718125],"genre_scores_gemma":[0.8207276,0.1565199,0.007731686,0.002051821,0.0004075548,0.0002183424,0.0005326184,0.00004632345,0.01176422],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002422629,"threshold_uncertainty_score":0.008104503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07551367413829047,"score_gpt":0.3739146006281771,"score_spread":0.2984009264898866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}