{"id":"W3164572170","doi":"10.3390/toxins13060378","title":"Therapeutic Uses of Bacterial Subunit Toxins","year":2021,"lang":"en","type":"review","venue":"Toxins","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Cholera toxin; Protein subunit; Biology; Shiga toxin; Endoplasmic-reticulum-associated protein degradation; Endoplasmic reticulum; Immunotoxin; Cell biology; Anthrax toxin; Fusion protein; Unfolded protein response; Biochemistry; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001977187,0.000355019,0.001140244,0.00007170306,0.00006269982,0.000029299,0.0004398855,0.0003528974,0.0002505809],"category_scores_gemma":[0.0002244051,0.000292992,0.0005313517,0.0002311491,0.000159362,0.000002226455,0.000484672,0.0002276962,0.00002096551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002891128,"about_ca_system_score_gemma":0.0006877412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001350281,"about_ca_topic_score_gemma":0.00007250805,"domain_scores_codex":[0.9982439,0.0003326423,0.0004189645,0.0004382475,0.0002174326,0.0003488528],"domain_scores_gemma":[0.9987988,0.0000666209,0.0002065539,0.0006945099,0.0001498559,0.00008365556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003311484,0.0003558435,0.00002328896,0.009392096,0.002354143,0.00002680065,0.00007256398,4.105522e-7,0.02372508,0.0003511935,0.00593737,0.9577281],"study_design_scores_gemma":[0.0001369047,0.000187742,0.00000908436,0.001021008,0.0002449999,0.00001232681,0.00002218587,2.001551e-7,0.001301232,0.000004018078,0.9967901,0.000270209],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005706678,0.996644,0.00002054013,0.00001605959,0.0002349761,0.0003721891,0.0001671093,0.00001172341,0.001962707],"genre_scores_gemma":[0.0002188307,0.9960328,0.0001429604,0.00003442771,0.0005306246,0.00009013495,0.0004920602,0.00006442831,0.002393751],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9908527,"threshold_uncertainty_score":0.9999522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07551367413829047,"score_gpt":0.3739146006281771,"score_spread":0.2984009264898866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}