{"id":"W3164776430","doi":"10.1007/978-3-030-67696-4_9","title":"Cancer Biology of the Endoplasmic Reticulum Lectin Chaperones Calreticulin, Calnexin and PDIA3/ERp57","year":2021,"lang":"en","type":"review","venue":"Progress in molecular and subcellular biology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; BC Children's Hospital; University of British Columbia","funders":"","keywords":"Calnexin; Calreticulin; Biology; Endoplasmic reticulum; Cell biology; Immunogenic cell death; Chaperone (clinical); Cancer research; Cancer cell; Cancer; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005652948,0.0007647225,0.000964561,0.001322038,0.0001990609,0.0009540842,0.000731311,0.0008095102,0.001866757],"category_scores_gemma":[0.0004815074,0.0002454083,0.0002824751,0.001982038,0.0003738594,0.0009816567,0.0006749643,0.001269814,0.001451122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009551475,"about_ca_system_score_gemma":0.001104685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00153392,"about_ca_topic_score_gemma":0.002722967,"domain_scores_codex":[0.9998773,0.00001495335,0.00001392479,0.00002145208,0.00005451132,0.00001783949],"domain_scores_gemma":[0.9998307,0.00004995862,0.00002553428,0.000006681654,0.00006453679,0.00002265321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001330779,0.00005506829,0.0001724832,0.009340541,0.00007505325,0.0001555401,0.00003616554,0.000474179,0.00393574,0.005466558,0.05291185,0.9272438],"study_design_scores_gemma":[0.00002162257,0.00005667483,0.0005893112,0.0008106107,0.00006098731,0.0004693249,0.00001967265,0.00007896961,0.0009483287,0.001073431,0.995861,0.00001011782],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001100137,0.9988161,0.00009342675,0.0002116769,0.0001598153,0.000002676385,0.00001618985,0.000005308029,0.0005849271],"genre_scores_gemma":[0.0004868213,0.9985703,0.0001032217,0.0001162421,0.00009750709,0.000003596856,0.00003676625,8.966563e-7,0.0005845819],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001866757,"threshold_uncertainty_score":0.006930113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361071436412046,"score_gpt":0.3136289997737335,"score_spread":0.300018285409613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}