{"id":"W3164788343","doi":"10.1136/annrheumdis-2021-eular.56","title":"POS0086 ANALYSIS OF DISEASE ACTIVITY MEASURES IN THE CONTEXT OF A METHOTREXATE WITHDRAWAL STUDY AMONG PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH TOFACITINIB 11 MG ONCE DAILY + METHOTREXATE: POST HOC ANALYSIS OF DATA FROM ORAL SHIFT","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pfizer (Canada); Université Laval; Montreal Clinical Research Institute","funders":"","keywords":"Tofacitinib; Medicine; Rheumatoid arthritis; Methotrexate; Internal medicine; Post-hoc analysis; Placebo; Context (archaeology); Clinical endpoint; Confidence interval; Surgery; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004090684,0.001058542,0.002628321,0.0004750107,0.0004577294,0.0009100595,0.0007069585,0.0006945834,0.00443765],"category_scores_gemma":[0.005609691,0.0003033679,0.003958674,0.0005487974,0.0005164529,0.0009124094,0.0007081709,0.001549569,0.0003504571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004143317,"about_ca_system_score_gemma":0.0008881836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001203251,"about_ca_topic_score_gemma":0.002058572,"domain_scores_codex":[0.9953041,0.00304036,0.0002585527,0.0006541013,0.0003397347,0.0004032373],"domain_scores_gemma":[0.9954579,0.002687399,0.0006028127,0.0006023059,0.0002734729,0.0003760051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7684194,0.002639544,0.1776486,0.0004734732,0.01632042,0.0005649584,0.0002761625,0.001007177,0.009493458,0.000206129,0.0017207,0.02122993],"study_design_scores_gemma":[0.02413583,0.13616,0.8163654,0.00005264841,0.009805497,0.0004953435,0.000589268,0.005885097,0.003215752,0.0003233952,0.002864037,0.0001076832],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983563,0.0002561455,0.0003048965,0.00004449507,0.00008813958,0.00006869523,0.0005252477,0.00001475389,0.0003413502],"genre_scores_gemma":[0.9971159,0.0000796376,0.0003627978,0.00005954719,0.00007516023,0.0001881888,0.001053266,0.0000148821,0.001050732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00443765,"threshold_uncertainty_score":0.02163386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04874233966477513,"score_gpt":0.3270796538001049,"score_spread":0.2783373141353297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}