{"id":"W3164843014","doi":"10.1136/annrheumdis-2021-eular.2678","title":"AB0559 EFFICACY AND SAFETY OF RISANKIZUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS AFTER INADEQUATE RESPONSE OR INTOLERANCE TO DMARDs: 24-WEEK RESULTS FROM THE PHASE 3, RANDOMIZED, DOUBLE-BLIND KEEPsAKE 1 TRIAL","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Probity Medical Research","funders":"","keywords":"Medicine; Psoriatic arthritis; Randomized controlled trial; Psoriasis; Double blind; Physical therapy; Internal medicine; Arthritis; Dermatology; Alternative medicine; Pathology; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001975548,0.001709115,0.003496726,0.0004467406,0.0005540799,0.001442532,0.0008937185,0.002152898,0.004598938],"category_scores_gemma":[0.001623666,0.0007333289,0.00290408,0.0003728905,0.001258998,0.001417295,0.0004081061,0.003392639,0.001340294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000585721,"about_ca_system_score_gemma":0.00086391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000844817,"about_ca_topic_score_gemma":0.001803722,"domain_scores_codex":[0.9993007,0.0003331437,0.00005535571,0.0001272943,0.00006725732,0.0001161415],"domain_scores_gemma":[0.9989179,0.000317259,0.0002749864,0.0001096948,0.00006249494,0.0003177083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9729076,0.003573465,0.001017971,0.0005301891,0.001281615,0.00006018619,0.00005921389,0.0002700303,0.003585395,0.00007848637,0.0008331811,0.01580262],"study_design_scores_gemma":[0.9488022,0.04588488,0.003482435,0.00002690845,0.0005479072,0.00004934056,0.00002666271,0.0003416068,0.0003907916,0.00009945143,0.0003275634,0.00002026758],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901854,0.005679202,0.0003067113,0.0005688625,0.0004020455,0.0005993173,0.0008485166,0.0001225527,0.00128735],"genre_scores_gemma":[0.9916733,0.002412594,0.0007090393,0.001072083,0.0004349746,0.0005896161,0.00119222,0.00003005596,0.001886172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004598938,"threshold_uncertainty_score":0.01538503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04448913930741695,"score_gpt":0.3339838451042612,"score_spread":0.2894947057968443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}