{"id":"W3164843014","doi":"10.1136/annrheumdis-2021-eular.2678","title":"AB0559 EFFICACY AND SAFETY OF RISANKIZUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS AFTER INADEQUATE RESPONSE OR INTOLERANCE TO DMARDs: 24-WEEK RESULTS FROM THE PHASE 3, RANDOMIZED, DOUBLE-BLIND KEEPsAKE 1 TRIAL","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Probity Medical Research","funders":"","keywords":"Medicine; Psoriatic arthritis; Randomized controlled trial; Psoriasis; Double blind; Physical therapy; Internal medicine; Arthritis; Dermatology; Alternative medicine; Pathology; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.001100942,0.000239511,0.00119302,0.0001134838,0.00009571206,0.00003618339,0.0002492677,0.00006614927,0.0002042195],"category_scores_gemma":[0.009489584,0.0001242688,0.000183469,0.0006360019,0.0004127198,0.0001607394,0.0001809697,0.0002142064,0.000006252663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002532787,"about_ca_system_score_gemma":0.0007753859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002481777,"about_ca_topic_score_gemma":0.00009257949,"domain_scores_codex":[0.9962219,0.001168449,0.00120945,0.0003425071,0.0007578169,0.0002998994],"domain_scores_gemma":[0.9947808,0.003318965,0.0004691381,0.0008380013,0.0004426143,0.0001504621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8837963,0.001820573,0.0001800511,0.00011294,0.0004642641,0.00001888541,0.003874528,0.00003569863,0.000002927103,0.000008282656,0.000453793,0.1092317],"study_design_scores_gemma":[0.8988575,0.001474702,0.09333683,0.004173447,0.0002187254,0.000001295507,0.0008739624,0.00008334778,0.0004487557,0.0001474309,0.0002240099,0.0001600019],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900757,0.002325164,0.00001591315,0.003152687,0.00009580391,0.00368112,0.0005973848,0.00001004394,0.00004617197],"genre_scores_gemma":[0.9977427,0.001403709,0.0000434335,0.0002986601,0.00002199117,0.0002608441,0.00007719879,0.00002428483,0.0001271987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1090717,"threshold_uncertainty_score":0.9988539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04448913930741695,"score_gpt":0.3339838451042612,"score_spread":0.2894947057968443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}