{"id":"W3164878902","doi":"10.1161/hypertensionaha.121.17267","title":"Induction of the PPARγ (Peroxisome Proliferator-Activated Receptor γ)-GCM1 (Glial Cell Missing 1) Syncytialization Axis Reduces sFLT1 (Soluble fms-Like Tyrosine Kinase 1) in the Preeclamptic Placenta","year":2021,"lang":"en","type":"article","venue":"Hypertension","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Receptor tyrosine kinase; Peroxisome proliferator-activated receptor; Receptor; Preeclampsia; Placenta; Tyrosine kinase; Peroxisome proliferator-activated receptor gamma; Chemistry; Peroxisome; Internal medicine; Endocrinology; Cell biology; Medicine; Biology; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001538523,0.0002133726,0.0003591695,0.0002740468,0.0001610911,0.0002730247,0.0002041753,0.0002907773,0.001375051],"category_scores_gemma":[0.0001292376,0.0001945907,0.000366735,0.0001949577,0.0002529301,0.0001535899,0.0002066184,0.0009749137,0.0003050673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003035931,"about_ca_system_score_gemma":0.0004086161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001285425,"about_ca_topic_score_gemma":0.001874632,"domain_scores_codex":[0.999822,0.00002145746,0.00002490928,0.0000369727,0.00003950114,0.00005525348],"domain_scores_gemma":[0.9999026,0.00001705689,0.00002542695,0.000009709208,0.00001027597,0.00003495526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004081125,0.00005780383,0.0001414448,0.00005086058,0.000005263719,0.00004805731,0.0000312149,0.00004434126,0.9981477,0.00007338334,0.00005819573,0.000933596],"study_design_scores_gemma":[0.00004383928,0.0007173533,0.004332189,0.000007759887,0.00002778837,0.0001652968,0.00007203708,0.0005605822,0.9913606,0.00004830998,0.002659503,0.000004741415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939674,0.001464678,0.002152643,0.0002152059,0.00006558191,0.00004220744,0.0005087321,0.0001095637,0.001474063],"genre_scores_gemma":[0.9903892,0.001704241,0.002241968,0.0001457122,0.00001315929,0.00008637132,0.0009266047,0.00003188293,0.004460935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001375051,"threshold_uncertainty_score":0.004599988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03291935200994069,"score_gpt":0.2480431980664443,"score_spread":0.2151238460565036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}