{"id":"W3164890381","doi":"10.1016/j.ygyno.2021.05.010","title":"Prognostic significance of T cells, PD-L1 immune checkpoint and tumour associated macrophages in clear cell carcinoma of the ovary","year":2021,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Kingston Health Sciences Centre; Hospital for Sick Children; SickKids Foundation; Queen's University","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Ontario Ministry of Research, Innovation and Science","keywords":"FOXP3; Immune system; Immune checkpoint; Tissue microarray; Cytotoxic T cell; CD20; CD8; Medicine; Cancer research; CD68; T cell; Immunotherapy; Immunohistochemistry; Pathology; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000570795,0.000144819,0.0006044479,0.00006375166,0.00004310803,0.000003509445,0.0001369913,0.0002460557,0.0003143597],"category_scores_gemma":[0.0004336988,0.0001052281,0.0001482575,0.0004138846,0.0003594605,0.00002138566,0.0001255126,0.0002886445,0.000002485613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000253944,"about_ca_system_score_gemma":0.0006333981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002664911,"about_ca_topic_score_gemma":0.0002445077,"domain_scores_codex":[0.998336,0.0003744469,0.00060028,0.0002726349,0.0001397125,0.0002769181],"domain_scores_gemma":[0.9985819,0.0005964596,0.0003979398,0.0002500798,0.0001330143,0.00004061138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008949891,0.001002749,0.1346133,0.0001972438,0.00005941548,0.0002231954,0.0003977862,0.000006017476,0.8601941,0.000008515077,0.0001813454,0.002221388],"study_design_scores_gemma":[0.002518818,0.001358593,0.6430524,0.00003949754,0.00006502577,0.00002504531,0.0005242653,0.00002452462,0.3518748,0.00004583073,0.000403792,0.00006741137],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912978,0.004426738,0.000001640475,0.001052696,0.0003269326,0.0005743593,0.00002027555,0.00001219251,0.002287401],"genre_scores_gemma":[0.9982842,0.0004619168,0.0002751158,0.0003160992,0.00001880947,0.00003474691,0.000008688636,0.00001317431,0.0005872741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5084391,"threshold_uncertainty_score":0.4291077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0142763318829228,"score_gpt":0.2546512290902594,"score_spread":0.2403748972073366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}