{"id":"W3164946860","doi":"10.1002/cam4.4185","title":"Inhibition of lipid metabolism exerts antitumor effects on rhabdomyosarcoma","year":2021,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Children's Cancer Association of Japan; Cancer Research Institute","keywords":"Rhabdomyosarcoma; Lipid metabolism; Warburg effect; Glycolysis; Apoptosis; Metabolism; Fatty acid metabolism; Beta oxidation; Cancer research; Chemistry; Cell growth; Endocrinology; Biology; Internal medicine; Hexokinase; Biochemistry; Medicine; Sarcoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321585,0.0001755353,0.0003805436,0.00006200782,0.00004238843,0.000004237387,0.00008470043,0.0001051088,0.0001406066],"category_scores_gemma":[0.0001773271,0.0001482154,0.00009542461,0.0001834793,0.0001257181,0.000003908224,0.00005204516,0.0001005797,0.000004106403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001462345,"about_ca_system_score_gemma":0.000175833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004698529,"about_ca_topic_score_gemma":0.00003317275,"domain_scores_codex":[0.9988731,0.00006739137,0.0002427834,0.0003619497,0.0002300152,0.0002247168],"domain_scores_gemma":[0.9991795,0.00002311742,0.0001154922,0.000379255,0.0001851326,0.0001174933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001166643,0.00004776232,0.0001333676,0.000137183,0.00005837401,0.000009478518,0.00009271719,0.000008245123,0.9285362,0.00018273,0.03499986,0.0356774],"study_design_scores_gemma":[0.00150366,0.0001312893,0.003489172,0.0002003929,0.00006742094,0.00001271802,0.00003135206,0.000001908586,0.6338317,0.00004328439,0.3605811,0.0001059694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9271673,0.06194921,0.0002625887,0.001334619,0.005516613,0.0002195622,0.00003369064,0.00001600159,0.003500394],"genre_scores_gemma":[0.9731402,0.01157245,0.0001190907,0.002439301,0.01077695,0.00006555954,0.000141954,0.00003107912,0.001713351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3255813,"threshold_uncertainty_score":0.6044047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009020121156916779,"score_gpt":0.2655783622217223,"score_spread":0.2565582410648055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}