{"id":"W3164946860","doi":"10.1002/cam4.4185","title":"Inhibition of lipid metabolism exerts antitumor effects on rhabdomyosarcoma","year":2021,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Children's Cancer Association of Japan; Cancer Research Institute","keywords":"Rhabdomyosarcoma; Lipid metabolism; Warburg effect; Glycolysis; Apoptosis; Metabolism; Fatty acid metabolism; Beta oxidation; Cancer research; Chemistry; Cell growth; Endocrinology; Biology; Internal medicine; Hexokinase; Biochemistry; Medicine; Sarcoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001285844,0.0003999153,0.0003108303,0.0002925199,0.0001146157,0.0001080979,0.0001225588,0.0001421636,0.0006120373],"category_scores_gemma":[0.00005292911,0.00008473061,0.0001896521,0.0001368963,0.0001576673,0.0001144236,0.0001151891,0.0003670779,0.0001351685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001437564,"about_ca_system_score_gemma":0.0002117619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004483201,"about_ca_topic_score_gemma":0.001127147,"domain_scores_codex":[0.9999337,0.00001428796,0.000006102723,0.000009282718,0.00001372185,0.00002286029],"domain_scores_gemma":[0.9999548,0.000008483766,0.00001212194,0.000005872566,0.000004269987,0.00001439986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000264938,0.0001052401,0.000169673,0.00003405989,0.000005722796,0.00003133253,0.000009893775,0.00013995,0.9970144,0.00006175954,0.000034928,0.002128086],"study_design_scores_gemma":[0.0000460203,0.001426989,0.00406005,0.000005436998,0.00002045938,0.00009676412,0.00001286062,0.0005965617,0.9926804,0.00003539291,0.001015507,0.000003572437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963497,0.001424457,0.0007298311,0.00005940075,0.00001290516,0.00002496291,0.0001537559,0.00006041661,0.001184517],"genre_scores_gemma":[0.9965997,0.001280318,0.0008468192,0.00002284623,0.000006803478,0.00003501891,0.0002985056,0.000009798336,0.0009003436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006120373,"threshold_uncertainty_score":0.002047539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009020121156916779,"score_gpt":0.2655783622217223,"score_spread":0.2565582410648055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}