{"id":"W3164994466","doi":"10.1007/s12013-021-00998-7","title":"Monovalent: Divalent Anion Selectivity in the CFTR Channel Pore","year":2021,"lang":"en","type":"article","venue":"Cell Biochemistry and Biophysics","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Divalent; Chemistry; Biophysics; Selectivity; Extracellular; Mutant; Intracellular; Patch clamp; Membrane; Biochemistry; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003962449,0.0001610693,0.0002693535,0.0003524442,0.0004444001,0.000913999,0.0005589222,0.000795413,0.00270511],"category_scores_gemma":[0.0005438668,0.0001043717,0.0001455315,0.0001805417,0.0005746739,0.001194176,0.0008224193,0.0004794722,0.0004272784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000410807,"about_ca_system_score_gemma":0.0003569504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004893596,"about_ca_topic_score_gemma":0.0006893727,"domain_scores_codex":[0.9997424,0.00003703582,0.00002220415,0.0000676702,0.00008778514,0.00004278767],"domain_scores_gemma":[0.9997423,0.00007924012,0.0000456874,0.00001383901,0.00004886011,0.00007009254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001000255,0.00003311003,0.001950328,0.0002221277,0.000009652667,0.0002338725,0.0001254484,0.0001868092,0.9748526,0.01109976,0.0004384132,0.009847515],"study_design_scores_gemma":[0.0002832152,0.000835275,0.02180162,0.00007763717,0.00006257591,0.004801993,0.0009556307,0.007262003,0.925301,0.02334493,0.01519949,0.00007461965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977649,0.005639628,0.009974753,0.00190301,0.0001582302,0.00001868867,0.0002243806,0.0001362671,0.004295908],"genre_scores_gemma":[0.9963458,0.0009546095,0.0009860366,0.0002887573,0.00004874955,0.000005219169,0.00009316191,0.00001671909,0.001261018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00270511,"threshold_uncertainty_score":0.009049475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0118362265584057,"score_gpt":0.2612453013293059,"score_spread":0.2494090747709002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}