{"id":"W3165013340","doi":"10.1038/s41385-021-00414-6","title":"T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet","year":2021,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Abbotsford Veterinary Clinic","funders":"National Health and Medical Research Council; National Cancer Institute; Medical Research Council; Hunter Medical Research Institute","keywords":"Biology; Phenotype; Interleukin 22; Lineage (genetic); Innate lymphoid cell; Cell biology; Transcription factor; Cellular differentiation; Immunology; Immune system; Acquired immune system; Interleukin; Genetics; Gene; Cytokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002067897,0.0003242729,0.0002952202,0.0004797753,0.0003398492,0.0008735249,0.0001693983,0.0002479822,0.002269197],"category_scores_gemma":[0.0002128023,0.0002493057,0.0002380355,0.0002583749,0.0002500546,0.0003724693,0.0004360371,0.0009575037,0.0007169474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001361124,"about_ca_system_score_gemma":0.0001793735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002060931,"about_ca_topic_score_gemma":0.0005099183,"domain_scores_codex":[0.9996446,0.00006266996,0.00002541162,0.00005465942,0.00006924407,0.0001434597],"domain_scores_gemma":[0.9997751,0.00002453212,0.00005935974,0.00002204297,0.00004372753,0.00007518967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003019134,0.0000299309,0.004125786,0.00002989927,0.000007333904,0.0002888691,0.0001356177,0.00002234684,0.9916838,0.0002210928,0.00006419678,0.00308918],"study_design_scores_gemma":[0.0001017897,0.001316968,0.2085595,0.00006114211,0.00009542629,0.004273128,0.001492979,0.001276889,0.7648198,0.0008453531,0.01712603,0.00003098942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954388,0.001216891,0.00112832,0.00003871629,0.00002542915,0.00002609736,0.0001534127,0.00003414596,0.00193827],"genre_scores_gemma":[0.9929778,0.0006883743,0.0008781062,0.00005996522,0.00004049865,0.0000388899,0.0003550268,0.00003890021,0.004922558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002269197,"threshold_uncertainty_score":0.007591248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006560987865745499,"score_gpt":0.200826516719583,"score_spread":0.1942655288538375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}