{"id":"W3165029898","doi":"10.1186/s13567-021-00952-8","title":"Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) moonlights as an adhesin in Mycoplasma hyorhinis adhesion to epithelial cells as well as a plasminogen receptor mediating extracellular matrix degradation","year":2021,"lang":"en","type":"article","venue":"Veterinary Research","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Jiangsu Agricultural Science and Technology Independent Innovation Fund; Six Talent Peaks Project in Jiangsu Province; Jiangsu Agricultural Science and Technology Innovation Fund; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China; Jiangsu Academy of Agricultural Sciences","keywords":"Glyceraldehyde 3-phosphate dehydrogenase; Biology; Plasmin; Extracellular matrix; Fibronectin; Laminin; Molecular biology; Western blot; Bacterial adhesin; Microbiology; Cell biology; Biochemistry; Dehydrogenase; Enzyme; Virulence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001158759,0.0002867075,0.0001690869,0.0002323678,0.0001636284,0.0003019137,0.0001258172,0.0003127673,0.0008351639],"category_scores_gemma":[0.00007999442,0.00008387006,0.0003142048,0.0001953401,0.000206784,0.0001815447,0.0002390626,0.0002969039,0.0002815717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000293826,"about_ca_system_score_gemma":0.0001725207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007246987,"about_ca_topic_score_gemma":0.0008982654,"domain_scores_codex":[0.9998412,0.00002887938,0.0000145377,0.00002975917,0.0000397902,0.00004579348],"domain_scores_gemma":[0.9999471,0.000005777259,0.00001584232,0.00000616991,0.00001340531,0.00001182717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008846309,0.00001672766,0.0009136339,0.00009097278,0.000006285101,0.000166146,0.00002366866,0.00003275348,0.9961058,0.0001052388,0.00009734039,0.002352882],"study_design_scores_gemma":[0.000006734006,0.000148498,0.02073863,0.00001378379,0.00002241573,0.0005511304,0.000173584,0.0006134216,0.9729702,0.0001313108,0.004623463,0.000006724739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976878,0.01370378,0.004850189,0.0005720786,0.0001671208,0.00003022984,0.0004691465,0.0001391726,0.003190246],"genre_scores_gemma":[0.9934531,0.002285602,0.001519732,0.00007663087,0.00001534668,0.00001214138,0.0002673556,0.000006299382,0.002363703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008351639,"threshold_uncertainty_score":0.002793849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04876468979225942,"score_gpt":0.3615044802576817,"score_spread":0.3127397904654223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}