{"id":"W3165032238","doi":"10.3390/cells10061354","title":"Transcriptionally Active Chromatin—Lessons Learned from the Chicken Erythrocyte Chromatin Fractionation","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Chromatin; Biology; Histone; Histone-modifying enzymes; Histone code; Chromatin remodeling; Nucleosome; ChIA-PET; Histone H1; Cell biology; Genetics; DNA; Computational biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00112945,0.0007345824,0.001099114,0.001427667,0.0002619385,0.001156948,0.000902257,0.001444942,0.0009200375],"category_scores_gemma":[0.0008091766,0.0004664164,0.0003880674,0.0009925129,0.001549904,0.001872277,0.0008246094,0.003408719,0.00108493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001477989,"about_ca_system_score_gemma":0.000744909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00225688,"about_ca_topic_score_gemma":0.002091009,"domain_scores_codex":[0.999799,0.00003375539,0.0000254097,0.00005704053,0.00006487506,0.00002002582],"domain_scores_gemma":[0.9995102,0.0002276991,0.00003180933,0.00002972254,0.0001528878,0.00004772364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001810779,0.00006666937,0.0002756556,0.007918899,0.00009533485,0.0004969846,0.0001951838,0.0009420427,0.01798277,0.02490425,0.03857665,0.9083645],"study_design_scores_gemma":[0.00002057343,0.0000886921,0.0007461736,0.0008816163,0.00003696267,0.001030976,0.00004571504,0.0001603116,0.002565457,0.004413302,0.9899852,0.00002495423],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001957294,0.9977521,0.0003819973,0.0006606081,0.0003054964,0.000002010078,0.000009884567,0.000006839686,0.0006852176],"genre_scores_gemma":[0.001874518,0.9954365,0.0005166007,0.0007681305,0.000383138,0.000006652593,0.00003445267,0.000005474377,0.0009746163],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00225688,"threshold_uncertainty_score":0.01072359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05823461173107181,"score_gpt":0.331770895483545,"score_spread":0.2735362837524732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}