{"id":"W3165032238","doi":"10.3390/cells10061354","title":"Transcriptionally Active Chromatin—Lessons Learned from the Chicken Erythrocyte Chromatin Fractionation","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Chromatin; Biology; Histone; Histone-modifying enzymes; Histone code; Chromatin remodeling; Nucleosome; ChIA-PET; Histone H1; Cell biology; Genetics; DNA; Computational biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001666803,0.0004069023,0.000663923,0.00005060711,0.0002010038,0.00007798398,0.0003334077,0.0007116647,0.0005300152],"category_scores_gemma":[0.00006547764,0.0003351506,0.0005821549,0.0002043406,0.00008882481,0.000009960923,0.00008460607,0.0003994302,0.0001164795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760067,"about_ca_system_score_gemma":0.0007146639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006302482,"about_ca_topic_score_gemma":0.0001084341,"domain_scores_codex":[0.9978831,0.0003529527,0.0004942931,0.0007164611,0.000316975,0.0002362024],"domain_scores_gemma":[0.9985374,0.0001228599,0.0004825756,0.0006473539,0.0001438162,0.00006601273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000159409,0.00006714443,1.541923e-7,0.0004922113,0.0007646767,0.000002200859,0.0001041021,0.0001466955,0.04337387,0.00005021469,0.01342505,0.9415577],"study_design_scores_gemma":[0.0002531887,0.00003405636,0.00003821727,0.001475893,0.0005317919,0.00001515996,0.00003336874,0.00002862666,0.012087,0.00006711623,0.9850829,0.000352658],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004229903,0.9952922,0.0008764691,0.000496259,0.0008410479,0.0006672523,0.000650106,0.00002845132,0.000725179],"genre_scores_gemma":[0.0003409715,0.9848499,0.0003290761,0.00009408449,0.001528865,0.0001520274,0.01103083,0.00008403304,0.001590155],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9716579,"threshold_uncertainty_score":0.9999101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05823461173107181,"score_gpt":0.331770895483545,"score_spread":0.2735362837524732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}