{"id":"W3165299249","doi":"10.1136/annrheumdis-2021-eular.2735","title":"POS0186 METABOLOMIC SIGNATURES FOR KNEE CARTILAGE VOLUME LOSS OVER 10 YEARS","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"European Regional Development Fund; National Health and Medical Research Council; Instituto de Salud Carlos III; Medical Research Council; Canadian Institutes of Health Research","keywords":"Medicine; Cartilage; Osteoarthritis; Body mass index; Population; Prospective cohort study; Internal medicine; Cohort; Metabolite; Metabolomics; Pathology; Bioinformatics; Anatomy; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003397127,0.0004426755,0.0005492512,0.0006924658,0.0002773455,0.0008194462,0.0002393945,0.0008750841,0.006181894],"category_scores_gemma":[0.0006213739,0.0001496813,0.0006761595,0.0008619833,0.0002273332,0.0003802784,0.0005203531,0.0005755525,0.00151152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001765033,"about_ca_system_score_gemma":0.000219674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008826202,"about_ca_topic_score_gemma":0.001483569,"domain_scores_codex":[0.9997215,0.00003808799,0.00003292182,0.00008188283,0.00006995858,0.00005574995],"domain_scores_gemma":[0.9996303,0.00005693407,0.0001470209,0.00002434354,0.00007403131,0.0000672625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02995722,0.0005582642,0.6841233,0.0007950983,0.001919932,0.001535356,0.0002148186,0.0008414229,0.1786411,0.0004557752,0.006447415,0.09451029],"study_design_scores_gemma":[0.0001179921,0.001718696,0.9761874,0.00006446944,0.0004919814,0.001549947,0.0002823797,0.0008547703,0.01127049,0.0006154719,0.00678622,0.00006002764],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9693374,0.005763063,0.0009187199,0.0005206218,0.0003389833,0.00004086197,0.01933737,0.00009609485,0.003646831],"genre_scores_gemma":[0.9818096,0.001256831,0.000869562,0.0006034771,0.0001820306,0.00006306008,0.009932866,0.00003137632,0.005251289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006181894,"threshold_uncertainty_score":0.02068049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02132885455934154,"score_gpt":0.2907250151956536,"score_spread":0.2693961606363121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}