{"id":"W3165306967","doi":"10.1136/annrheumdis-2021-eular.3972","title":"OP0040 HIPPOCAMPAL IMMUNE CELL TRAFFICKING AND A MYELOID PREDOMINANT INFLAMMATORY RESPONSE WITH ENHANCED ANTIGEN PRESENTATION AND DECREASED LEVELS OF NEUROTRANSMITTERS UNDERLY THE NEUROPSYCHIATRIC PHENOTYPE OF THE NZW/NZB MURINE LUPUS MODEL","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National and Kapodistrian University of Athens","keywords":"Immune system; Systemic lupus erythematosus; Immunology; Medicine; Hippocampus; Phenotype; Hippocampal formation; Internal medicine; Biology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001481779,0.0008382781,0.0004795435,0.0007769616,0.0002818558,0.0006228674,0.0004412767,0.0007729075,0.004052971],"category_scores_gemma":[0.0002018429,0.0002684616,0.0003209644,0.0002396389,0.0009395128,0.0006234047,0.0003513919,0.001822471,0.0007307109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004105394,"about_ca_system_score_gemma":0.0004905325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00142827,"about_ca_topic_score_gemma":0.002028852,"domain_scores_codex":[0.9997473,0.00002296134,0.00002456558,0.00005414624,0.00008712842,0.00006393459],"domain_scores_gemma":[0.9997444,0.00001559212,0.00008412277,0.00003121285,0.00002483174,0.00009989979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000597474,0.0000920285,0.0002728046,0.00004962544,0.000008494851,0.0003414814,0.00003247658,0.00004377989,0.9970775,0.0002465261,0.00008862802,0.001149299],"study_design_scores_gemma":[0.0002461718,0.001402723,0.01840232,0.00002363286,0.00006211093,0.002829267,0.0002453178,0.0007151873,0.9718894,0.0006831763,0.003478613,0.00002204254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933038,0.0007092338,0.00235156,0.0004115702,0.00009327131,0.00003231718,0.0009552977,0.0001600866,0.001982821],"genre_scores_gemma":[0.9863063,0.0007246538,0.00263076,0.0001692316,0.00003096342,0.00009896944,0.0009056531,0.00008327785,0.009050211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004052971,"threshold_uncertainty_score":0.01355851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02564788542950463,"score_gpt":0.2782988585480861,"score_spread":0.2526509731185814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}