{"id":"W3165414811","doi":"10.1002/jcph.1914","title":"Influence of Prednisone on Inflammatory Biomarkers in Community‐Acquired Pneumonia: Secondary Analysis of a Randomized Trial","year":2021,"lang":"en","type":"article","venue":"The Journal of Clinical Pharmacology","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact","funders":"Gottfried und Julia Bangerter-Rhyner-Stiftung; Inselspital, Universitätsspital Bern; Universität Basel; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Helmut Horten Stiftung; National Science Foundation; Nora van Meeuwen Häfliger Stiftung","keywords":"Prednisone; Medicine; Procalcitonin; Placebo; Internal medicine; Pneumonia; Community-acquired pneumonia; Gastroenterology; Randomized controlled trial; Glucocorticoid; Corticosteroid; Absolute neutrophil count; Immunology; Pathology; Chemotherapy; Neutropenia; Sepsis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009797795,0.0001355676,0.002772882,0.0003903081,0.00003453109,0.000002503338,0.0002322654,0.0001471137,0.0003142009],"category_scores_gemma":[0.003357961,0.00008170666,0.001143293,0.0006130214,0.0005804592,0.00004927383,0.00007835755,0.0006805024,0.000001696341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004876637,"about_ca_system_score_gemma":0.0005502754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004896983,"about_ca_topic_score_gemma":0.00003187349,"domain_scores_codex":[0.9899844,0.006330397,0.003102944,0.00009896513,0.0003324907,0.0001508122],"domain_scores_gemma":[0.9790404,0.01814388,0.001952117,0.0002988224,0.0004392252,0.0001255603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9148645,0.00578648,0.03345298,0.00006366528,0.02697507,0.0002034434,0.0006521401,0.003202812,0.01291934,0.00001352293,0.0004852579,0.001380724],"study_design_scores_gemma":[0.7023724,0.002567799,0.267429,0.0001498125,0.01574394,0.00002853169,0.0002103644,0.0002846572,0.01097692,0.00009869691,0.00007861188,0.00005934416],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953927,0.001025494,0.000002678897,0.002454661,0.000387101,0.0005100101,0.000008591323,0.000003085103,0.0002156159],"genre_scores_gemma":[0.9956742,0.002594021,0.00005095678,0.001519797,0.0001241586,0.00001254888,0.000004251842,0.000008634034,0.00001144067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.233976,"threshold_uncertainty_score":0.4020036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1035798270811201,"score_gpt":0.4627796006136836,"score_spread":0.3591997735325635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}