{"id":"W3165507113","doi":"10.1038/s41389-021-00334-x","title":"MMP8 increases tongue carcinoma cell–cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5","year":2021,"lang":"en","type":"article","venue":"Oncogenesis","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Centre for Blood Research, University of British Columbia; Syöpäjärjestöt; Academy of Finland; Oulun Yliopisto; Medical Research Center Oulu; Helsingin Yliopisto","keywords":"Cell adhesion; Matrix metalloproteinase; Cancer research; Cell migration; Cell; Cleavage (geology); Motility; Cell biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007474388,0.0002432795,0.0001901343,0.0001213773,0.0001092419,0.0002024071,0.0001074986,0.0001835793,0.001487287],"category_scores_gemma":[0.00007735975,0.0000917555,0.0002002008,0.000103233,0.0001206846,0.0001174518,0.0001321276,0.0003471301,0.0002654511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000213941,"about_ca_system_score_gemma":0.0001262023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008859002,"about_ca_topic_score_gemma":0.001145078,"domain_scores_codex":[0.999928,0.000006927999,0.000007867194,0.0000168262,0.00002170344,0.00001863612],"domain_scores_gemma":[0.9999579,0.000006970927,0.00001222644,0.000005314137,0.000005843121,0.0000116797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004411761,0.00001375049,0.0001638563,0.00002716675,0.000003025577,0.0000207471,0.000008984954,0.00001516886,0.9988503,0.00001598884,0.00002900478,0.0008078315],"study_design_scores_gemma":[0.00001009956,0.000252587,0.007175424,0.000004662225,0.00001686857,0.0001990387,0.00002892392,0.0005492815,0.9900066,0.00001346782,0.001740467,0.000002480009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973037,0.0008903556,0.0008639174,0.00004340821,0.00001106065,0.00001510821,0.0001822076,0.00004453994,0.0006457146],"genre_scores_gemma":[0.9953726,0.0006260257,0.00128037,0.00003160831,0.000004556388,0.00001990445,0.0004997688,0.00001007778,0.002155171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001487287,"threshold_uncertainty_score":0.004975438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006843257939286562,"score_gpt":0.208264683580374,"score_spread":0.2014214256410874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}