{"id":"W3165618543","doi":"10.3724/sp.j.1123.2020.03001","title":"[Determination of the binding of natural products to the human c-myb oncogene promoter G-quadruplex DNA by capillary electrophoresis and electrospray ionization mass spectrometry].","year":2020,"lang":"en","type":"article","venue":"PubMed","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; MYB; Electrospray ionization; Capillary electrophoresis; G-quadruplex; Transcription factor; DNA; Mass spectrometry; Molecular biology; Chromatography; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004537139,0.000571846,0.0002216693,0.0009294651,0.0003289228,0.0001656619,0.0004622368,0.0006014609,0.001697618],"category_scores_gemma":[0.0009959546,0.000348264,0.0002582077,0.0004329593,0.0003322142,0.0002918596,0.0002352334,0.0005010494,0.0007727974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004588466,"about_ca_system_score_gemma":0.0004112782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001238698,"about_ca_topic_score_gemma":0.0017964,"domain_scores_codex":[0.9995694,0.00008259404,0.00002701683,0.000156473,0.0001228637,0.00004170497],"domain_scores_gemma":[0.9994281,0.0002125282,0.000166459,0.00003938637,0.0001039984,0.00004954888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003579004,0.00001593767,0.0001401006,0.00003791681,0.000006692504,0.00002207405,0.0000164544,0.00007072641,0.9974167,0.0001056007,0.00007011274,0.002061951],"study_design_scores_gemma":[0.000009922298,0.0001351433,0.002220664,0.000006865494,0.000006252731,0.0001802952,0.00001453447,0.002129207,0.9936434,0.00008672208,0.001556703,0.00001019493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8126352,0.003892098,0.1721361,0.0003031075,0.0001047841,0.0004623338,0.003951409,0.00173018,0.004784729],"genre_scores_gemma":[0.7982074,0.002854366,0.1797924,0.0003369438,0.00003642108,0.0006889891,0.007922808,0.0001790707,0.009981656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001697618,"threshold_uncertainty_score":0.005679131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006429616960119299,"score_gpt":0.1962908723756421,"score_spread":0.1898612554155228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}