{"id":"W3165619198","doi":"10.1136/gutjnl-2020-323219","title":"Decoy bypass for appetite suppression in obese adults: role of synergistic nutrient sensing receptors GPR84 and FFAR4 on colonic endocrine cells","year":2021,"lang":"en","type":"article","venue":"Gut","topic":"Bariatric Surgery and Outcomes","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"School of Pharmacy, University College London; Biotechnology and Biological Sciences Research Council; Wellcome; Directorate for Biological Sciences; University College London; Wellcome Trust; Bowel and Cancer Research","keywords":"Enteroendocrine cell; Receptor; Endocrinology; Internal medicine; Ghrelin; Chemistry; Hormone; Peptide YY; GPR120; Appetite; Nutrient sensing; Biology; Neuropeptide Y receptor; Signal transduction; Medicine; Endocrine system; Neuropeptide; Biochemistry; G protein-coupled receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001551564,0.0001211762,0.0003597277,0.0001100423,0.00003639933,0.000007373765,0.00003011401,0.00007101277,0.00006857237],"category_scores_gemma":[0.0004658923,0.0001039766,0.00007774393,0.0001877186,0.00003046792,0.0000354778,0.00004341904,0.0001235724,0.000007044555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005119459,"about_ca_system_score_gemma":0.00008145767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005338216,"about_ca_topic_score_gemma":0.00002511015,"domain_scores_codex":[0.9989996,0.00006009567,0.0003045814,0.0002566412,0.0001449723,0.0002341027],"domain_scores_gemma":[0.9988875,0.000647036,0.00008438455,0.0002068272,0.00008292769,0.0000913198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0118559,0.002725964,0.1497797,0.004630294,0.0003967956,0.001346399,0.00437171,0.0002644912,0.6936704,0.005392117,0.0147265,0.1108397],"study_design_scores_gemma":[0.00808229,0.0005864077,0.01711607,0.002861825,0.0001880004,0.00008396518,0.001651384,0.002832399,0.8843744,0.0005181103,0.08136038,0.0003448048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968268,0.001221498,0.00008110583,0.0006712629,0.000541603,0.0003077154,0.00001904676,0.00001858068,0.0003123536],"genre_scores_gemma":[0.9975969,0.0004338333,0.001052976,0.0001670099,0.0001063566,0.000008475175,0.00004373976,0.00001675175,0.0005740013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.190704,"threshold_uncertainty_score":0.4240044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007459039097823035,"score_gpt":0.2479217871515022,"score_spread":0.2404627480536791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}