{"id":"W3165677176","doi":"10.1002/biof.1760","title":"Cip2A modulates osteogenic differentiation via the ERK‐Runx2 pathway in MG63 cells","year":2021,"lang":"en","type":"article","venue":"BioFactors","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Daegu University","keywords":"RUNX2; Osteoblast; MAPK/ERK pathway; Cell biology; Gene knockdown; Protein phosphatase 2; Phosphatase; Chemistry; Alkaline phosphatase; Kinase; Phosphorylation; Downregulation and upregulation; Transcription factor; Cellular differentiation; Biology; Biochemistry; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002632329,0.0006164811,0.0005109135,0.0001479168,0.0002426841,0.0001942769,0.0005663233,0.0005510081,0.00002779151],"category_scores_gemma":[0.001096911,0.0004982346,0.0004804659,0.0005036605,0.0001779247,0.00003243049,0.0004195616,0.0003145878,0.0001235417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004218989,"about_ca_system_score_gemma":0.000259842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001103153,"about_ca_topic_score_gemma":0.0001362153,"domain_scores_codex":[0.9965699,0.0003568833,0.0006387744,0.001025705,0.0004670434,0.000941713],"domain_scores_gemma":[0.9976854,0.0003649177,0.000307018,0.001086531,0.0002017697,0.0003543307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003471746,0.0003717087,0.04217296,0.0000782767,0.0001495702,0.0000261906,0.00050183,0.0001038133,0.9488431,0.00006984086,0.006565958,0.001113324],"study_design_scores_gemma":[0.0008207331,0.00008721898,0.1543816,0.00002453735,0.00009502294,0.00001016138,0.00103131,0.0001000589,0.7670078,0.000230496,0.07613277,0.00007832462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857813,0.0107458,0.0002805153,0.00004381188,0.001156505,0.0004538869,0.000361775,0.00007089227,0.001105529],"genre_scores_gemma":[0.9929357,0.00110741,0.00009367162,0.0003546973,0.0005440754,0.00007224942,0.001002162,0.00009707678,0.003792914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1818353,"threshold_uncertainty_score":0.9997469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008436223869681668,"score_gpt":0.2077751141139207,"score_spread":0.1993388902442391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}