{"id":"W3165677176","doi":"10.1002/biof.1760","title":"Cip2A modulates osteogenic differentiation via the ERK‐Runx2 pathway in MG63 cells","year":2021,"lang":"en","type":"article","venue":"BioFactors","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Daegu University","keywords":"RUNX2; Osteoblast; MAPK/ERK pathway; Cell biology; Gene knockdown; Protein phosphatase 2; Phosphatase; Chemistry; Alkaline phosphatase; Kinase; Phosphorylation; Downregulation and upregulation; Transcription factor; Cellular differentiation; Biology; Biochemistry; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001319119,0.0003375738,0.0003048989,0.0004494722,0.0003383857,0.0003973371,0.0001452121,0.0002735797,0.001280684],"category_scores_gemma":[0.00009211574,0.0001554001,0.0002979244,0.0004867597,0.0003606854,0.0002331841,0.0001928024,0.0006035656,0.0003640061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003645301,"about_ca_system_score_gemma":0.0003845198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002911807,"about_ca_topic_score_gemma":0.004065136,"domain_scores_codex":[0.9998251,0.00001736673,0.00001777159,0.00002329046,0.00007281355,0.00004373405],"domain_scores_gemma":[0.9999483,0.000007043391,0.00001374688,0.000006122393,0.000009876137,0.0000149715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001157806,0.00003339997,0.0002381375,0.0000565848,0.000005759651,0.00008308222,0.00001667103,0.00007475101,0.9982418,0.00008324457,0.0001041484,0.0009467765],"study_design_scores_gemma":[0.0000373789,0.0001528507,0.009727307,0.000005357098,0.00002090172,0.0002865581,0.00006141085,0.001350308,0.983628,0.00006142889,0.004661319,0.000007205367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908897,0.00241744,0.001711187,0.0003027282,0.00004664704,0.00004572239,0.001089258,0.0001312555,0.003365991],"genre_scores_gemma":[0.9934071,0.001210314,0.001128979,0.00008360173,0.00001438857,0.00007274106,0.001062291,0.00001815116,0.003002235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002911807,"threshold_uncertainty_score":0.005789697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008436223869681668,"score_gpt":0.2077751141139207,"score_spread":0.1993388902442391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}