{"id":"W3165807938","doi":"10.1136/annrheumdis-2021-eular.1323","title":"OP0022 RHO EXPRESSION FACILITATES T CELL MIGRATION TO LYMPH NODES IN RESPONSE INFLAMMATION","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Pfizer; Eli Lilly and Company","keywords":"RAC1; RHOA; Inflammation; Transcriptome; Arthritis; Cytotoxic T cell; Immunology; CDC42; T cell; Molecular biology; CD43; Medicine; Spleen; Lymph; Cell biology; Gene expression; Biology; Gene; Pathology; Immune system; Signal transduction; In vitro; Genetics; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001301401,0.0002526462,0.0001852309,0.0002648677,0.000350114,0.0006088243,0.0001656875,0.0003966924,0.005790229],"category_scores_gemma":[0.0001660074,0.0001535246,0.0003451162,0.0001325395,0.0002979996,0.0002697053,0.0003347736,0.001352151,0.001342991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002320817,"about_ca_system_score_gemma":0.0004295073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000521473,"about_ca_topic_score_gemma":0.00114181,"domain_scores_codex":[0.9997304,0.00004448587,0.000008993145,0.00002690122,0.00004861792,0.0001406612],"domain_scores_gemma":[0.9999232,0.000009331055,0.00001607786,0.00000725614,0.000009196182,0.00003489684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001032126,0.0001064762,0.0006955393,0.0001385449,0.00001000618,0.0002201748,0.00005101451,0.00009242301,0.9924286,0.0006717666,0.0005998114,0.003953481],"study_design_scores_gemma":[0.0002701455,0.001252881,0.06057091,0.00007929534,0.0000990383,0.001085849,0.0009201615,0.004237405,0.9074955,0.0007711371,0.02319134,0.00002641148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851289,0.002288098,0.002336403,0.0006118171,0.0001715672,0.00004075893,0.000518446,0.0001079946,0.008796042],"genre_scores_gemma":[0.9880847,0.000969191,0.001036557,0.0001677123,0.00003720692,0.00007306958,0.0007006111,0.00003049661,0.008900528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005790229,"threshold_uncertainty_score":0.01937026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03822556029863239,"score_gpt":0.3145342865716119,"score_spread":0.2763087262729795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}