{"id":"W3165807938","doi":"10.1136/annrheumdis-2021-eular.1323","title":"OP0022 RHO EXPRESSION FACILITATES T CELL MIGRATION TO LYMPH NODES IN RESPONSE INFLAMMATION","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Pfizer; Eli Lilly and Company","keywords":"RAC1; RHOA; Inflammation; Transcriptome; Arthritis; Cytotoxic T cell; Immunology; CDC42; T cell; Molecular biology; CD43; Medicine; Spleen; Lymph; Cell biology; Gene expression; Biology; Gene; Pathology; Immune system; Signal transduction; In vitro; Genetics; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115743,0.00009895313,0.0002064271,0.000116644,0.00005839956,0.00002249089,0.00008340884,0.00002903053,0.0002342768],"category_scores_gemma":[0.002006335,0.00007050983,0.0001472899,0.0002699772,0.00002541205,0.0001246754,0.00006071578,0.00005009101,0.00002937937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002434214,"about_ca_system_score_gemma":0.0001563848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006912094,"about_ca_topic_score_gemma":0.00001229323,"domain_scores_codex":[0.9989009,0.0002011528,0.0003759692,0.0001487384,0.0002467094,0.000126498],"domain_scores_gemma":[0.9988958,0.0003450364,0.0001151781,0.0003493532,0.0002053279,0.00008936105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001544293,0.0006509588,0.01506446,0.0005428912,0.00003787622,0.00001049921,0.003120827,0.002334739,0.9604949,0.00005504244,0.005173536,0.01096998],"study_design_scores_gemma":[0.0004977884,0.00006795374,0.2675548,0.002036192,0.00003205435,0.000005231832,0.001181743,0.0007359445,0.7265927,0.0003861113,0.0008209773,0.00008839525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920525,0.0004870217,0.00008976833,0.006781868,0.00008831121,0.0002102538,0.00006341218,0.00001997016,0.0002069282],"genre_scores_gemma":[0.9986783,0.0001051535,0.0002216192,0.0002900865,0.00001784937,0.00003644224,0.00003454749,0.000009331475,0.0006066543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2524904,"threshold_uncertainty_score":0.2875308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03822556029863239,"score_gpt":0.3145342865716119,"score_spread":0.2763087262729795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}