{"id":"W3165817137","doi":"10.1136/annrheumdis-2021-eular.873","title":"AB0107 CHANGES IN EXTRACELLULAR MATRIX BIOMARKER C3M CORRELATE WITH ABATACEPT RESPONSE IN SEROPOSITIVE EARLY RA","year":2021,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; Canadian Institutes of Health Research; Regeneron Pharmaceuticals; Gilead Sciences; Sanofi; Amgen; Pfizer; Patient-Centered Outcomes Research Institute; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Medicine; Abatacept; Biomarker; Internal medicine; Population; Adalimumab; Rheumatoid arthritis; Gastroenterology; Immunology; Oncology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003258826,0.0003326106,0.0002822743,0.0006370328,0.0002801821,0.0005477998,0.0001964185,0.0004922731,0.002963066],"category_scores_gemma":[0.0009244234,0.0001590297,0.0002532867,0.0003458892,0.0001936143,0.0001927258,0.0001245608,0.0005003697,0.0004751388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001848563,"about_ca_system_score_gemma":0.0001391897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008693459,"about_ca_topic_score_gemma":0.0009891221,"domain_scores_codex":[0.9997714,0.00005432708,0.0000263039,0.00003701888,0.0000593919,0.00005152235],"domain_scores_gemma":[0.9993198,0.0002311546,0.0002241128,0.00003532044,0.00008863365,0.0001010106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004572001,0.0004949352,0.9258049,0.0001187861,0.0002335239,0.001561672,0.000167172,0.0002191414,0.04340575,0.00008507857,0.0006393419,0.02269763],"study_design_scores_gemma":[0.00003712425,0.0007400079,0.9933885,0.00002156062,0.00008945249,0.002096975,0.0001210875,0.0005043697,0.002271652,0.0000927068,0.0006269292,0.000009482155],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977201,0.0008153243,0.00008738285,0.00004304764,0.00002566029,0.000007994164,0.0001286707,0.00001378659,0.00115802],"genre_scores_gemma":[0.9991254,0.00009978301,0.0001036702,0.00004765503,0.00002410495,0.000006792224,0.0001267642,0.000002235282,0.0004635672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002963066,"threshold_uncertainty_score":0.009912431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02202277313827624,"score_gpt":0.2958334194159276,"score_spread":0.2738106462776514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}