{"id":"W3165871079","doi":"10.1039/d1an00698c","title":"Electrochemical flow injection analysis of the interaction between pyrroloquinoline quinone (PQQ) and α-synuclein peptides related to Parkinson's disease","year":2021,"lang":"en","type":"article","venue":"The Analyst","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto; Toronto Public Health","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Pyrroloquinoline quinone; Parkinson's disease; Chemistry; Electrochemistry; Disease; Flow injection analysis; Quinone; Biochemistry; Chromatography; Medicine; Pathology; Enzyme; Electrode; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005465642,0.0004786797,0.0004467608,0.0003640587,0.0001821605,0.0003319235,0.0005713843,0.0008327172,0.0005911092],"category_scores_gemma":[0.0004186765,0.00015511,0.0002593866,0.0003091923,0.000251506,0.0003617959,0.0001799971,0.0004677329,0.0001728242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003463659,"about_ca_system_score_gemma":0.0002301803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005916751,"about_ca_topic_score_gemma":0.0005950165,"domain_scores_codex":[0.9996185,0.00006752922,0.00001978824,0.0001111216,0.0001480082,0.00003497864],"domain_scores_gemma":[0.9997302,0.0001181574,0.00004893081,0.00001018785,0.00007478947,0.00001767107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001152839,0.0000619514,0.0005562534,0.00005879952,0.0000116803,0.00008070729,0.00004032927,0.00008812437,0.9949792,0.00007520429,0.00007557975,0.003856873],"study_design_scores_gemma":[0.00001616609,0.000371445,0.00304939,0.000007472883,0.00002451538,0.0002527736,0.00003649595,0.007656324,0.9877901,0.00006411509,0.0007161138,0.0000150888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9349955,0.003175979,0.05874691,0.000253863,0.0002038874,0.000160703,0.0006179093,0.0005744246,0.001270836],"genre_scores_gemma":[0.9564731,0.001742948,0.03840399,0.0003989601,0.00005266396,0.0001670161,0.0003923716,0.00002216361,0.002346831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008327172,"threshold_uncertainty_score":0.002890527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01289441184144813,"score_gpt":0.2707109720389459,"score_spread":0.2578165601974978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}