{"id":"W3165871245","doi":"10.4049/jimmunol.2001436","title":"RALDH Activity Induced by Bacterial/Fungal Pathogens in CD16+ Monocyte-Derived Dendritic Cells Boosts HIV Infection and Outgrowth in CD4+ T Cells","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal; Université Laval; Centre hospitalier de l'Université Laval; Montreal Clinical Research Institute; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Zymosan; Biology; TLR2; Immunology; Lipoteichoic acid; Cell biology; Microbiology; Staphylococcus aureus; Immune system; TLR4; In vitro; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008408973,0.0002347492,0.0002699508,0.0001009174,0.0001056646,0.0002911848,0.0001012862,0.0001664981,0.00149361],"category_scores_gemma":[0.00007043875,0.00009803788,0.0002167295,0.00009001288,0.0001053865,0.0000876881,0.0001646958,0.0006365693,0.0004699446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001555117,"about_ca_system_score_gemma":0.0001992071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004456281,"about_ca_topic_score_gemma":0.000784838,"domain_scores_codex":[0.9998803,0.00001968982,0.00001237603,0.00002001935,0.00001857441,0.00004896822],"domain_scores_gemma":[0.9999443,0.000007652765,0.000009389221,0.000008852878,0.000008156058,0.00002165085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003235801,0.00007573389,0.0003469972,0.00006204169,0.000004163275,0.0000373913,0.00001541259,0.00006305665,0.9974344,0.00003217128,0.00007306361,0.001532046],"study_design_scores_gemma":[0.00010055,0.001628015,0.007426784,0.0000147651,0.00003167673,0.0002118234,0.00008364137,0.001288173,0.9858146,0.00005433458,0.003339625,0.000005941792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969709,0.0006845815,0.0008053601,0.00008071552,0.00005028813,0.00003978772,0.0003740068,0.00004814795,0.0009462996],"genre_scores_gemma":[0.9958775,0.000351746,0.00116651,0.00006099164,0.00002450332,0.00004195966,0.0003831115,0.000009422247,0.002084375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00149361,"threshold_uncertainty_score":0.004996598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350451865404659,"score_gpt":0.2427520898113192,"score_spread":0.2292475711572726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}