{"id":"W3165874565","doi":"10.1371/journal.ppat.1009617","title":"The RyfA small RNA regulates oxidative and osmotic stress responses and virulence in uropathogenic Escherichia coli","year":2021,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Ottawa Hospital Research Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Microbiology; Fimbria; Escherichia coli; Biology; Pilus; Virulence; Biofilm; Transcriptome; Bacterial adhesin; Oxidative stress; Gene; Mutant; Bacteria; Gene expression; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001006461,0.0002896175,0.0001670972,0.0001915385,0.0001323239,0.0002173,0.0001197534,0.0002698399,0.0006286012],"category_scores_gemma":[0.0001711154,0.0001071381,0.0001950085,0.00007172587,0.0002132229,0.0001054937,0.0001980439,0.0002843609,0.0002451473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001555807,"about_ca_system_score_gemma":0.0001378664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005422292,"about_ca_topic_score_gemma":0.0005941059,"domain_scores_codex":[0.9998993,0.0000210631,0.000007064883,0.000021511,0.00002499848,0.00002605779],"domain_scores_gemma":[0.9998678,0.00002984622,0.00004372712,0.00001042364,0.00001798877,0.00003011553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004762999,0.000006504659,0.0001849323,0.000007380148,8.904659e-7,0.00002659983,0.000006639033,0.00001805704,0.9994084,0.00001698759,0.000009769465,0.0002662322],"study_design_scores_gemma":[0.00001343478,0.0002436834,0.04675885,0.00001234956,0.00001674595,0.0003198389,0.00009101867,0.001412822,0.9497865,0.00008538109,0.001248513,0.00001084304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968658,0.0008665691,0.001517165,0.00007908178,0.00001751595,0.000008903687,0.0001765173,0.00004451665,0.0004239799],"genre_scores_gemma":[0.9969765,0.0003400921,0.0009677684,0.00005196293,0.000006318613,0.0000153732,0.0002734067,0.0000150824,0.001353524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006286012,"threshold_uncertainty_score":0.002102852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01843852842762282,"score_gpt":0.2500382897877351,"score_spread":0.2315997613601122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}