{"id":"W3165874565","doi":"10.1371/journal.ppat.1009617","title":"The RyfA small RNA regulates oxidative and osmotic stress responses and virulence in uropathogenic Escherichia coli","year":2021,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Ottawa Hospital Research Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Microbiology; Fimbria; Escherichia coli; Biology; Pilus; Virulence; Biofilm; Transcriptome; Bacterial adhesin; Oxidative stress; Gene; Mutant; Bacteria; Gene expression; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003600781,0.0001987291,0.0001993982,0.00003401174,0.0002651129,0.00008137585,0.0001657119,0.000101154,0.000003868299],"category_scores_gemma":[0.001728638,0.0001591772,0.00004312122,0.0002097279,0.0003467621,0.000005800149,0.0005443342,0.0001812577,0.000002176328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001743134,"about_ca_system_score_gemma":0.0001528006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001159636,"about_ca_topic_score_gemma":0.0004858668,"domain_scores_codex":[0.9982193,0.0004980974,0.0002104239,0.0005098592,0.0001658109,0.0003965133],"domain_scores_gemma":[0.999009,0.0002548776,0.00006593994,0.0003881812,0.000171482,0.0001105419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001369302,0.00007521603,0.01611667,0.00004144785,0.00007858912,0.0000827976,0.0002208196,0.000003382759,0.9819617,0.00007929315,0.00001919704,0.001183963],"study_design_scores_gemma":[0.0005203737,0.0002504972,0.2122722,0.00007734892,0.00004170719,0.00001795944,0.001042972,0.0003323987,0.7842476,0.0001960379,0.000720469,0.0002803841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871843,0.0118705,0.00001971774,0.0003469493,0.00003017373,0.0002402813,0.00007950581,0.00001097222,0.0002176038],"genre_scores_gemma":[0.9879345,0.009871051,0.001162931,0.0001179674,0.00006129855,0.00007317798,0.00001751875,0.00002617777,0.0007354358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.197714,"threshold_uncertainty_score":0.6491058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01843852842762282,"score_gpt":0.2500382897877351,"score_spread":0.2315997613601122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}