{"id":"W3165926603","doi":"10.1200/jco.2021.39.15_suppl.e16131","title":"PRIME-HCC: Phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma.","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada","keywords":"Medicine; Hepatocellular carcinoma; Nivolumab; Ipilimumab; Internal medicine; Gastroenterology; Adverse effect; Hazard ratio; Cirrhosis; Oncology; Liver cancer; Surgery; Cancer; Immunotherapy; Confidence interval","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002113072,0.002469214,0.002291231,0.0006250247,0.0003428101,0.001004489,0.001194674,0.001578587,0.004494472],"category_scores_gemma":[0.0007522351,0.0009070479,0.001012183,0.0004659778,0.001413312,0.0009734214,0.0005825987,0.003436368,0.001382919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001157223,"about_ca_system_score_gemma":0.002484664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001157124,"about_ca_topic_score_gemma":0.003013353,"domain_scores_codex":[0.9995388,0.0002177431,0.00002344261,0.00006819602,0.00005147367,0.0001003241],"domain_scores_gemma":[0.9992403,0.00009991715,0.0001272283,0.00006747875,0.00002844056,0.0004365963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7027696,0.1734427,0.005871414,0.00107652,0.0007123082,0.0003224903,0.0002364492,0.002166012,0.03412203,0.0002972349,0.003750017,0.07523306],"study_design_scores_gemma":[0.4415239,0.5460879,0.005027092,0.00002586957,0.0002102931,0.0003169389,0.00004087045,0.0006058948,0.003957981,0.0001079674,0.002072223,0.00002308143],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884963,0.00200435,0.0005579023,0.0004068603,0.0002031584,0.004673852,0.001255152,0.0001538502,0.002248581],"genre_scores_gemma":[0.980732,0.002136795,0.002603975,0.001002277,0.0003263679,0.005194086,0.003741449,0.00003809761,0.004224847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004494472,"threshold_uncertainty_score":0.01503545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2571842839796477,"score_gpt":0.4511039821290246,"score_spread":0.193919698149377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}