{"id":"W3165994429","doi":"10.1128/spectrum.00127-21","title":"Presence of the Hmq System and Production of 4-Hydroxy-3-Methyl-2-Alkylquinolines Are Heterogeneously Distributed between Burkholderia cepacia Complex Species and More Prevalent among Environmental than Clinical Isolates","year":2021,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Institut National de la Recherche Scientifique","funders":"Canada Research Chairs; Government of Canada; Canadian Institutes of Health Research; Menzies School of Health Research; Northern Arizona University","keywords":"Quorum sensing; Burkholderia cepacia complex; Burkholderia; Biology; Microbiology; Bacteria; Pathogenicity; Pseudomonas aeruginosa; Biofilm; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002052633,0.0002746596,0.0002741835,0.0009555398,0.0002061762,0.0004296782,0.0001746259,0.0002867625,0.001855946],"category_scores_gemma":[0.001004917,0.000165688,0.0001672757,0.0005878306,0.0002952942,0.0002203665,0.0003789114,0.0002147024,0.0002934207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001079396,"about_ca_system_score_gemma":0.0001826696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001922014,"about_ca_topic_score_gemma":0.001523733,"domain_scores_codex":[0.999324,0.00009494725,0.00007205627,0.0001504046,0.0002586717,0.00009995639],"domain_scores_gemma":[0.9989799,0.0001639958,0.0004423804,0.00004917973,0.0002156611,0.0001488245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001920563,0.00005060411,0.06377187,0.0001342144,0.0000411959,0.0002557718,0.0001918875,0.00002343719,0.9309902,0.00006694692,0.00005774825,0.004224074],"study_design_scores_gemma":[0.00001171436,0.0004995922,0.8045176,0.00002910961,0.0001264923,0.005542048,0.001060098,0.0002468691,0.1857871,0.000143412,0.002019755,0.00001616534],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972284,0.0008483346,0.000613826,0.00005829164,0.000007664583,0.0000160278,0.0004655637,0.00001411549,0.0007477098],"genre_scores_gemma":[0.9987518,0.0002050107,0.0003753432,0.00001240261,0.000007315504,0.000007742084,0.0003292141,0.000002554435,0.0003085618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001922014,"threshold_uncertainty_score":0.006208718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01505029493784519,"score_gpt":0.2336441701396003,"score_spread":0.2185938752017551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}