{"id":"W3165994429","doi":"10.1128/spectrum.00127-21","title":"Presence of the Hmq System and Production of 4-Hydroxy-3-Methyl-2-Alkylquinolines Are Heterogeneously Distributed between Burkholderia cepacia Complex Species and More Prevalent among Environmental than Clinical Isolates","year":2021,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Institut National de la Recherche Scientifique","funders":"Canada Research Chairs; Government of Canada; Canadian Institutes of Health Research; Menzies School of Health Research; Northern Arizona University","keywords":"Quorum sensing; Burkholderia cepacia complex; Burkholderia; Biology; Microbiology; Bacteria; Pathogenicity; Pseudomonas aeruginosa; Biofilm; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001533339,0.000184214,0.0003860896,0.00001851886,0.00009454897,0.0000126468,0.0001181471,0.0002278217,0.000006241003],"category_scores_gemma":[0.00005206682,0.0001422662,0.0001116473,0.00005285992,0.0009227116,0.000005125195,0.000350258,0.0001033123,3.459913e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001215799,"about_ca_system_score_gemma":0.00001961185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002077781,"about_ca_topic_score_gemma":0.00007891426,"domain_scores_codex":[0.9986124,0.0002310726,0.0004351129,0.0004673443,0.00003707829,0.0002169749],"domain_scores_gemma":[0.9992107,0.00002461914,0.0003290357,0.0003601974,0.00002912217,0.0000462999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000352755,0.00003066737,0.2909758,0.00006188731,0.00009617626,0.000001373931,0.00003197829,0.000002724927,0.7086652,0.000003542149,0.00005757685,0.0000378415],"study_design_scores_gemma":[0.0001837366,0.0001047049,0.3927416,0.00004797259,0.00004656308,0.0001002737,0.000183969,0.00000665639,0.6060008,0.000002361293,0.0004904297,0.00009099955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972132,0.001116393,0.00001466636,0.0004723204,0.0003016408,0.0002367702,0.0006326946,0.000007623665,0.00000466756],"genre_scores_gemma":[0.9988334,0.0003685444,0.0001144491,0.00001520589,0.0001920863,0.00000199433,0.0003871188,0.00001338429,0.00007377424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1026644,"threshold_uncertainty_score":0.5801448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01505029493784519,"score_gpt":0.2336441701396003,"score_spread":0.2185938752017551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}