{"id":"W3166227213","doi":"10.1183/16000617.0023-2021","title":"Future concepts in bronchodilation for COPD: dual-<i>versus</i>monotherapy","year":2021,"lang":"en","type":"review","venue":"European Respiratory Review","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Manchester Biomedical Research Centre; Genentech; National Institutes of Health; Glenmark Pharmaceuticals; Mylan; Regeneron Pharmaceuticals; Sunovion; York University; AstraZeneca; Dartmouth College; Chiesi Farmaceutici; CSL Behring; Gilead Sciences; Sanofi; American Thoracic Society; Pfizer; Biogen; GlaxoSmithKline; National Institute for Health and Care Research; Insmed; Veracyte; Teva Pharmaceutical Industries","keywords":"Bronchodilation; Medicine; COPD; Dual (grammatical number); Bronchodilator Agents; Intensive care medicine; Internal medicine; Bronchodilator; Asthma","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002168661,0.0009264619,0.00399998,0.0003334485,0.0001196792,0.00006453553,0.0004507432,0.0002684606,0.00140787],"category_scores_gemma":[0.0005979499,0.0007863009,0.001650168,0.001166767,0.0001822277,0.0001562104,0.0002001813,0.001157984,0.0006279837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00105922,"about_ca_system_score_gemma":0.002020833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001697362,"about_ca_topic_score_gemma":0.000004858266,"domain_scores_codex":[0.9922307,0.0030302,0.001824948,0.001436961,0.0007251005,0.0007521067],"domain_scores_gemma":[0.9963269,0.0004489463,0.0007309093,0.00163478,0.0003953934,0.0004630602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006659087,0.0001131329,0.00001126825,0.1699757,0.0001989808,0.0006064993,0.00001442902,1.242175e-7,9.25107e-7,0.0001429186,0.03324977,0.7956197],"study_design_scores_gemma":[0.002444651,0.0001690086,0.0001038028,0.1371722,0.001084741,0.00005140182,0.00001769367,9.037645e-7,3.838623e-7,0.000001297088,0.8584065,0.0005473733],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003483153,0.9835629,0.00001310841,0.0002122418,0.0009779916,0.00761047,0.0002396468,0.00009721683,0.007282873],"genre_scores_gemma":[3.170371e-7,0.9907191,0.0002111876,0.002545273,0.002803064,0.0005665186,0.001110928,0.0003714004,0.001672211],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8251567,"threshold_uncertainty_score":0.999505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1073933882071104,"score_gpt":0.4211041921774757,"score_spread":0.3137108039703653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}