{"id":"W3166282680","doi":"10.1080/19336896.2021.1933872","title":"Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues","year":2021,"lang":"en","type":"article","venue":"Prion","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Infectivity; Virology; Pregnancy; Andrology; Biology; Chemistry; Medicine; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008499808,0.0004586964,0.0002080239,0.000631017,0.0003090532,0.0003423736,0.0002928304,0.0005145925,0.0008601304],"category_scores_gemma":[0.00140977,0.0003612245,0.0001795752,0.0002713514,0.0005524555,0.0001949177,0.0001942493,0.0005040851,0.000385425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002072265,"about_ca_system_score_gemma":0.0001598947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001158211,"about_ca_topic_score_gemma":0.001790253,"domain_scores_codex":[0.999545,0.0001688479,0.00005152267,0.00008773417,0.00009233036,0.00005447933],"domain_scores_gemma":[0.9994949,0.0002432802,0.00007545776,0.00009211097,0.00006333544,0.00003088852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001240824,0.00003381349,0.004095535,0.00008203911,0.00001093558,0.001466425,0.0002281833,0.00006792186,0.9892589,0.0001061044,0.0000471026,0.004478908],"study_design_scores_gemma":[0.00001674917,0.0005132447,0.04398362,0.00005191473,0.00007148958,0.0135073,0.0001931414,0.001663279,0.9355291,0.000287653,0.004161992,0.00002048365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9499758,0.004325447,0.0392645,0.0002012572,0.00006219911,0.0002733638,0.0004110023,0.0002752311,0.005211181],"genre_scores_gemma":[0.9616605,0.002327134,0.03287882,0.0001293726,0.00001270637,0.0001028909,0.0005805863,0.00007272102,0.002235202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001158211,"threshold_uncertainty_score":0.004495144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0389806358151469,"score_gpt":0.2826482301293357,"score_spread":0.2436675943141888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}