{"id":"W3166324988","doi":"10.1016/j.cllc.2021.05.009","title":"Durvalumab After Concurrent Chemoradiotherapy in Elderly Patients With Unresectable Stage III Non–Small–Cell Lung Cancer (PACIFIC)","year":2021,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre","funders":"Genentech; Daiichi-Sankyo; Merck KGaA; Moffitt Cancer Center; Takeda Pharmaceuticals U.S.A.; Spectrum Pharmaceuticals; Sanofi; Novartis; Merck; GlaxoSmithKline; Eli Lilly and Company; Bristol-Myers Squibb; AstraZeneca; Roche; Astellas Pharma US; Boehringer Ingelheim; Amgen; Pfizer","keywords":"Durvalumab; Medicine; Chemoradiotherapy; Stage (stratigraphy); Lung cancer; Oncology; Internal medicine; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002673515,0.0001846967,0.0006262216,0.0001450464,0.0002329968,0.0003932574,0.0001796324,0.0002591607,0.0007390998],"category_scores_gemma":[0.0006955937,0.0001021135,0.000424958,0.0002573576,0.0001315944,0.0003225586,0.0001729702,0.0005403218,0.000126193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004842406,"about_ca_system_score_gemma":0.0006084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002152095,"about_ca_topic_score_gemma":0.008147208,"domain_scores_codex":[0.9998865,0.00002131823,0.00001245485,0.00002255651,0.0000224013,0.00003474572],"domain_scores_gemma":[0.9997786,0.00004368179,0.0000672769,0.0000104558,0.00001844602,0.00008158972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.04010095,0.0008230804,0.7184246,0.0006594158,0.001568868,0.003200419,0.0002093612,0.0006358405,0.009105308,0.0002626106,0.004263964,0.2207456],"study_design_scores_gemma":[0.003505306,0.01068065,0.9580393,0.0001987484,0.002499398,0.005781276,0.0003102644,0.001721813,0.00255716,0.0003187163,0.01435414,0.00003313902],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844278,0.01211555,0.0001280533,0.0004293568,0.0001214525,0.00003577445,0.0002167711,0.00001105512,0.002514332],"genre_scores_gemma":[0.9963939,0.002286288,0.0001355381,0.0002655593,0.00009249499,0.0000169608,0.0002683101,0.000002645714,0.000538332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002152095,"threshold_uncertainty_score":0.004279137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01887738721131567,"score_gpt":0.3471904455025281,"score_spread":0.3283130582912124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}