{"id":"W3166334656","doi":"10.3389/fmicb.2021.655228","title":"Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus","year":2021,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Diabetes Canada; University of Toronto","funders":"Higher Education Discipline Innovation Project; Department of Education of Guangdong Province; Guangdong Science and Technology Department; Department of Agriculture of Guangdong Province; National Natural Science Foundation of China","keywords":"Biology; Virus; Virology; Host (biology); Population; Viral evolution; Genetics; Influenza A virus subtype H5N1; Transmission (telecommunications); Influenza A virus; Gene; Evolutionary biology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002990128,0.0001700288,0.0002413211,0.0008100036,0.0003659478,0.0004072836,0.0002243759,0.0002770955,0.0005851126],"category_scores_gemma":[0.0004630383,0.0001152939,0.0002786918,0.0005314519,0.0001988444,0.0002668674,0.0002900488,0.0002268246,0.0001290423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000316411,"about_ca_system_score_gemma":0.000206755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001804388,"about_ca_topic_score_gemma":0.003106965,"domain_scores_codex":[0.9997883,0.00004436169,0.00001535288,0.00007449553,0.00003563766,0.00004185243],"domain_scores_gemma":[0.9998307,0.0000322645,0.00005421312,0.00001028201,0.00003703146,0.0000353472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003403047,0.00008430652,0.6494111,0.0001769481,0.0002467094,0.001327883,0.001106245,0.004534767,0.3194696,0.001012947,0.0003241989,0.02196493],"study_design_scores_gemma":[0.00001154018,0.0002587362,0.973713,0.00001986998,0.00009517039,0.0017242,0.0007679554,0.01341894,0.006281345,0.0005841664,0.003086853,0.00003821159],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986491,0.0002490932,0.0004712303,0.00001313827,0.000004839641,0.00000323165,0.00006298039,0.000006307479,0.0005401724],"genre_scores_gemma":[0.9990165,0.0001202012,0.0005194846,0.00001615723,0.000004829948,0.000003215967,0.0001858175,0.000005471211,0.0001283016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001804388,"threshold_uncertainty_score":0.003587842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0377641324810231,"score_gpt":0.325349277241233,"score_spread":0.2875851447602099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}