{"id":"W3166437541","doi":"10.1007/s10875-021-01068-6","title":"Harnessing Type I IFN Immunity Against SARS-CoV-2 with Early Administration of IFN-β","year":2021,"lang":"en","type":"editorial","venue":"Journal of Clinical Immunology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Center for Advancing Translational Sciences; National Human Genome Research Institute; Institut National de la Santé et de la Recherche Médicale; Fonds de Recherche du Québec - Santé; Vlaamse regering; KU Leuven; Fondation pour la Recherche Médicale; National Institute of Allergy and Infectious Diseases; Jeffrey Modell Foundation; Fisher Center for Alzheimer's Research Foundation; Agence Nationale de la Recherche; Mercatus Center, George Mason University; Rockefeller University; Institut des maladies génétiques Imagine; CSL Behring; Onderzoeksraad, KU Leuven; George Mason University; St. Giles Foundation; Yale University; SCOR Corporate Foundation for Science; National Institutes of Health; Vlaamse Instelling voor Technologisch Onderzoek; Fonds Wetenschappelijk Onderzoek; Howard Hughes Medical Institute; Georgia Clinical and Translational Science Alliance; Université de Paris","keywords":"Library science; Excellence; Translational science; Center of excellence; Political science; Medicine; Gerontology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.003380726,0.0004124387,0.002700309,0.0004288551,0.0001006415,0.00008031516,0.0007037565,0.00224899,0.00001659971],"category_scores_gemma":[0.01623238,0.0003127144,0.0007601129,0.0005555726,0.0008983458,0.0002222106,0.0002086878,0.006766259,0.00002837854],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001699024,"about_ca_system_score_gemma":0.01170653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001219244,"about_ca_topic_score_gemma":0.00007880657,"domain_scores_codex":[0.9932432,0.001071675,0.003354771,0.0004221072,0.001412483,0.0004957504],"domain_scores_gemma":[0.9871581,0.004028557,0.003039651,0.0008693022,0.004834643,0.00006970904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.09411705,0.006307042,0.01452707,0.001242732,0.01150091,0.009649177,0.0005576672,6.830718e-7,0.3016476,0.00004023032,0.4977632,0.06264656],"study_design_scores_gemma":[0.008740176,0.0172925,0.008554069,0.002459796,0.0009611803,0.0004014655,0.0002170068,0.00000798928,0.0592567,0.00008368304,0.9016312,0.0003942129],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"editorial","genre_scores_codex":[0.7240157,0.002906989,0.00006484214,0.0003231585,0.27136,0.0001949557,0.0000148531,0.00001676885,0.001102765],"genre_scores_gemma":[0.3415837,0.00165483,0.001438214,0.004668747,0.6500663,0.000009515343,0.0001108292,0.0001976269,0.0002702498],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.403868,"threshold_uncertainty_score":0.9999325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09706859679961584,"score_gpt":0.4578275475153595,"score_spread":0.3607589507157437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}