{"id":"W3166471899","doi":"10.1096/fasebj.2021.35.s1.01592","title":"Glycerol‐3‐phosphate phosphatase/ Pgp in Pancreatic ß‐cells Functions as a Glucose Excess Security Valve Preventing Oversecretion of Insulin Secretion and Glucotoxicity","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Diabetes Québec; McGill University","funders":"","keywords":"Internal medicine; Endocrinology; Insulin; Carbohydrate metabolism; In vivo; Chemistry; Islet; Pancreatic islets; Glucokinase; Ex vivo; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001399017,0.0005165283,0.0002747036,0.0002209434,0.0001663637,0.0006385333,0.0002525756,0.0003176181,0.000894813],"category_scores_gemma":[0.0001275649,0.0002213892,0.0002242782,0.0001698711,0.0004735955,0.0003994154,0.0004963808,0.0007626899,0.0003472554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002004621,"about_ca_system_score_gemma":0.0002039636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002694275,"about_ca_topic_score_gemma":0.0002691223,"domain_scores_codex":[0.999903,0.000008729956,0.000009280663,0.00002706846,0.00002758374,0.00002442444],"domain_scores_gemma":[0.99989,0.000007895003,0.00004215416,0.00001263383,0.000009127141,0.00003810716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001587686,0.00000860141,0.0002846158,0.000050118,0.000004489346,0.0000616379,0.000005780807,0.00003712669,0.9976789,0.0001030374,0.00003438252,0.001572506],"study_design_scores_gemma":[0.00003736501,0.000242884,0.0051904,0.00001420344,0.00002624821,0.0003312844,0.00003452955,0.0005318954,0.9908751,0.0002085073,0.00250133,0.0000063281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804491,0.00741837,0.00920263,0.0003946176,0.00009171163,0.0000310361,0.000366569,0.0004532737,0.001592544],"genre_scores_gemma":[0.9912481,0.003177258,0.003472995,0.0001007655,0.00002687012,0.00002844049,0.0002521636,0.00003720691,0.001656181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000894813,"threshold_uncertainty_score":0.002993464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01164818656236396,"score_gpt":0.2465051417122148,"score_spread":0.2348569551498508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}