{"id":"W3166499510","doi":"10.1101/2021.06.17.448756","title":"Presynaptic Mitochondrial Volume and Density Scale with Presynaptic Power Demand","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Oxidative phosphorylation; Bioenergetics; Mitochondrion; Glycolysis; Biophysics; Power density; Cell biology; Biochemistry; Biology; Chemistry; Power (physics); Metabolism; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001534915,0.0002205695,0.0002372188,0.0005621744,0.0002556167,0.0006057771,0.0003242228,0.000373539,0.005306473],"category_scores_gemma":[0.0006960177,0.0002573647,0.0001944548,0.0002986402,0.0003861578,0.0006747256,0.0005187463,0.0004162171,0.0007733635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004385348,"about_ca_system_score_gemma":0.0001127143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008228202,"about_ca_topic_score_gemma":0.001195535,"domain_scores_codex":[0.9998595,0.000007825531,0.00001347727,0.00004160992,0.00006066437,0.00001697752],"domain_scores_gemma":[0.9994972,0.0001228311,0.0001530353,0.00003645965,0.0001243298,0.00006624366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003026758,0.00003476053,0.03816024,0.00009571337,0.00003462071,0.0001104391,0.0001211335,0.001204635,0.9513053,0.00087408,0.0003058041,0.007450583],"study_design_scores_gemma":[0.00002138763,0.0002730697,0.7485906,0.00003421614,0.00003785465,0.0008018576,0.0003376582,0.01884822,0.228313,0.001677756,0.001030977,0.00003338642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905709,0.0005326727,0.005891351,0.0001053304,0.00001539102,0.00001189685,0.0007501258,0.00008878943,0.002033571],"genre_scores_gemma":[0.9974558,0.00008771391,0.001333744,0.00001393854,0.000008096648,0.00001004131,0.0003426175,0.00001568903,0.00073242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005306473,"threshold_uncertainty_score":0.01775193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005977795453823728,"score_gpt":0.1933302113910192,"score_spread":0.1873524159371955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}