{"id":"W3166568332","doi":"10.1038/s41586-021-03620-1","title":"A roadmap for the Human Developmental Cell Atlas","year":2021,"lang":"en","type":"article","venue":"Nature","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Medical Research Council; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; UK Research and Innovation; Wellcome Trust; Francis Crick Institute; Cancer Research UK","keywords":"Atlas (anatomy); Human cell; Human Protein Atlas; Biology; Organogenesis; Computational biology; Neuroscience; Bioinformatics; Genetics; Cell culture; Anatomy; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002597975,0.000983247,0.001122944,0.003612108,0.001188446,0.003471209,0.002450426,0.001128263,0.02661699],"category_scores_gemma":[0.0043654,0.0005649937,0.000801598,0.005207194,0.0005663783,0.002674041,0.003206142,0.002239184,0.01565048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002572085,"about_ca_system_score_gemma":0.006295654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01560005,"about_ca_topic_score_gemma":0.02726585,"domain_scores_codex":[0.9992294,0.000184305,0.00008138239,0.0001567066,0.0002470716,0.0001011754],"domain_scores_gemma":[0.9957267,0.0008907119,0.0001866281,0.0008572688,0.001458414,0.000880216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000313118,0.00006157722,0.002787102,0.001493805,0.000108127,0.0003696537,0.0003400022,0.002519003,0.01287085,0.07155197,0.6201202,0.2874647],"study_design_scores_gemma":[0.00001999241,0.00002439646,0.00292492,0.0002557592,0.00003829087,0.0002566877,0.0001258977,0.001402661,0.002242692,0.02036407,0.9723148,0.00002972992],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.009476653,0.03205521,0.3981832,0.02053479,0.003274969,0.0007445163,0.3746242,0.05335213,0.1077543],"genre_scores_gemma":[0.02974593,0.01909086,0.5276474,0.004564059,0.0007783608,0.001819036,0.3840407,0.005553516,0.02676007],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02661699,"threshold_uncertainty_score":0.08904272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048499216191018,"score_gpt":0.2449983205992273,"score_spread":0.2345133284373171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}