{"id":"W3166663256","doi":"10.15252/embr.202152986","title":"A critical relationship between bone and fat: the role of bone marrow adipose-derived RANKL in bone metabolism","year":2021,"lang":"en","type":"letter","venue":"EMBO Reports","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Adipose tissue; Bone remodeling; Bone marrow; RANKL; Metabolism; Endocrinology; Internal medicine; Biology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025036,0.0007014584,0.0014636,0.0004512635,0.001390218,0.002585371,0.001391284,0.02196955,0.003102819],"category_scores_gemma":[0.009218345,0.0004620771,0.0007100678,0.0003380305,0.003267072,0.002637665,0.001139576,0.0253705,0.002780299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002460041,"about_ca_system_score_gemma":0.001665258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220283,"about_ca_topic_score_gemma":0.001712894,"domain_scores_codex":[0.9987526,0.0003686786,0.0001673923,0.0001608516,0.000383254,0.0001671967],"domain_scores_gemma":[0.9958501,0.002675546,0.0002543557,0.0001729827,0.0005081914,0.0005387258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009054787,0.0001143165,0.0007918995,0.000279852,0.0000657587,0.007354421,0.0002220131,0.0002010582,0.003003145,0.01108058,0.9351708,0.04081076],"study_design_scores_gemma":[0.0005085826,0.0002198804,0.00169139,0.0002195862,0.00006651808,0.003918297,0.0004061963,0.0006563953,0.002095589,0.02971594,0.9604052,0.00009651796],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001008205,0.008421049,0.000199749,0.9539111,0.03500549,0.00001013817,0.00005029389,0.00002812278,0.001365905],"genre_scores_gemma":[0.02522503,0.01411843,0.0006446878,0.7171555,0.2337645,0.00005709297,0.00005085985,0.00003881724,0.008945112],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02196955,"threshold_uncertainty_score":0.01784897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01446154757001194,"score_gpt":0.2522470335258049,"score_spread":0.237785485955793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}