{"id":"W3166663256","doi":"10.15252/embr.202152986","title":"A critical relationship between bone and fat: the role of bone marrow adipose-derived RANKL in bone metabolism","year":2021,"lang":"en","type":"letter","venue":"EMBO Reports","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Adipose tissue; Bone remodeling; Bone marrow; RANKL; Metabolism; Endocrinology; Internal medicine; Biology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005002094,0.0003740014,0.0008751997,0.0001314402,0.0001011034,0.00006148491,0.0001059841,0.0008156477,0.00004451835],"category_scores_gemma":[0.001796247,0.0003138625,0.0002981306,0.000178699,0.0003373833,0.00001096893,0.0002571118,0.000721538,0.00000200353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008083973,"about_ca_system_score_gemma":0.0002064432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001258843,"about_ca_topic_score_gemma":0.00002851052,"domain_scores_codex":[0.9970834,0.0003625861,0.0009784172,0.0007622677,0.0003950789,0.0004182883],"domain_scores_gemma":[0.9981123,0.0001984684,0.0004039285,0.0009924116,0.0001725713,0.0001202745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002565843,0.0004717415,0.2163252,0.001374613,0.0007988065,0.01360129,0.0005326419,0.000007891895,0.2505956,0.0007896609,0.5084336,0.006812392],"study_design_scores_gemma":[0.000628993,0.00004361005,0.2274195,0.000152174,0.0008940084,0.000820498,0.00006875335,0.000001632171,0.02620141,0.005029916,0.7380773,0.0006622543],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.670912,0.2781427,0.00005415991,0.04783639,0.0005336528,0.0006241759,0.0002638972,0.00002933282,0.001603683],"genre_scores_gemma":[0.9789599,0.000405087,0.0002922031,0.01567694,0.002372134,0.00008302999,0.001408191,0.00007378443,0.0007287579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3080479,"threshold_uncertainty_score":0.9999313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01446154757001194,"score_gpt":0.2522470335258049,"score_spread":0.237785485955793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}