{"id":"W3166803911","doi":"10.1101/2021.05.30.446341","title":"Sex differences and estradiol effects in MAPK and Akt cell signalling across subregions of the hippocampus","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"University of British Columbia","keywords":"Dentate gyrus; Protein kinase B; Hippocampal formation; Ovariectomized rat; MAPK/ERK pathway; Phosphoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007094867,0.0002340501,0.0001832958,0.0003474659,0.0001080888,0.000215545,0.0001133734,0.0001385859,0.003111449],"category_scores_gemma":[0.00008683924,0.0001393934,0.0001701021,0.0001385233,0.000186337,0.0001999729,0.0001465862,0.0002572832,0.0003684978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001190465,"about_ca_system_score_gemma":0.0001417641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003593036,"about_ca_topic_score_gemma":0.0006817715,"domain_scores_codex":[0.9999205,0.000004584786,0.000006744202,0.00002956021,0.00001642494,0.00002212153],"domain_scores_gemma":[0.9999019,0.000006568979,0.0000384438,0.000007918338,0.00001485525,0.00003017986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002254977,0.00009212542,0.01129263,0.0001077274,0.00003576967,0.0002795956,0.00009516552,0.00003793569,0.9758674,0.0001469688,0.0001542178,0.009635547],"study_design_scores_gemma":[0.0001057582,0.002038493,0.4819928,0.00003450856,0.0001075219,0.001482255,0.000440666,0.0001726918,0.5087856,0.0003587222,0.004457604,0.00002333303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994732,0.002299991,0.0005318907,0.00008732719,0.0000373428,0.00001770965,0.0008002914,0.0000322253,0.001461315],"genre_scores_gemma":[0.9903384,0.002145327,0.0005199019,0.00007715542,0.00001955153,0.00005831956,0.0006594477,0.00001899939,0.006162803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003111449,"threshold_uncertainty_score":0.01040882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02041177676089856,"score_gpt":0.2575511915196071,"score_spread":0.2371394147587085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}