{"id":"W3166861630","doi":"10.82308/28814","title":"Studying complex traits in the post-GWAS era: application to asthma and allergy-related traits","year":2018,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Knut och Alice Wallenbergs Stiftelse; Canadian Institutes of Health Research; Tekes","keywords":"Genome-wide association study; Asthma; Medicine; Genetics; Biology; Immunology; Single-nucleotide polymorphism; Gene; Genotype","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0073394,0.001094582,0.001238656,0.002430297,0.0006019156,0.001930557,0.0007375863,0.001061543,0.00341257],"category_scores_gemma":[0.009685828,0.000395641,0.001417643,0.004255446,0.0008953047,0.0009511432,0.001560623,0.002772575,0.0005113836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006269971,"about_ca_system_score_gemma":0.001024936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002689329,"about_ca_topic_score_gemma":0.003438803,"domain_scores_codex":[0.9964111,0.002124768,0.0001306461,0.0006622037,0.000569335,0.0001018865],"domain_scores_gemma":[0.9913666,0.00557402,0.0007556471,0.001093473,0.0007575759,0.0004527395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0008058143,0.0004457426,0.3777485,0.00278521,0.004901292,0.001384272,0.001346177,0.004658239,0.03463606,0.01647363,0.01039789,0.5444173],"study_design_scores_gemma":[0.0003569369,0.002085976,0.8016429,0.0008951794,0.002902134,0.002814761,0.001036871,0.02154506,0.01218899,0.07181703,0.08244692,0.0002672002],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3941402,0.1665368,0.3855317,0.0295542,0.00247869,0.0007269074,0.007216236,0.001608865,0.01220632],"genre_scores_gemma":[0.6758273,0.05875811,0.2467789,0.008042944,0.002359496,0.0008922293,0.002191737,0.0002616558,0.004887515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0073394,"threshold_uncertainty_score":0.03881496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02135833569727889,"score_gpt":0.2637064550049276,"score_spread":0.2423481193076487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}