{"id":"W3167235221","doi":"10.1096/fasebj.27.1_supplement.672.2","title":"FUNCTIONAL ACTIVITY IN HUMAN HEART EXPRESSING CYP1A1","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Metabolite; Western blot; Microsome; Cytosol; Chemistry; Metabolism; Monoclonal antibody; Human heart; Biochemistry; Active metabolite; Molecular biology; Pharmacology; Biology; Antibody; Enzyme; Internal medicine; Medicine; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003545394,0.0002556874,0.0002906767,0.000219459,0.0001759116,0.0003636055,0.0001365825,0.0002380146,0.003021657],"category_scores_gemma":[0.0002990407,0.0001371493,0.0002855209,0.0003203569,0.000137095,0.000143505,0.0001572586,0.0004586262,0.001369891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002583904,"about_ca_system_score_gemma":0.0001226085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000905447,"about_ca_topic_score_gemma":0.0006710406,"domain_scores_codex":[0.9996948,0.00006227357,0.00002623162,0.0001014856,0.00007232738,0.00004283618],"domain_scores_gemma":[0.9998841,0.0000372693,0.00002005943,0.00002011612,0.00002590949,0.00001261413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002135895,0.00005074018,0.0008825352,0.00007887528,0.00001558897,0.00007298264,0.00003284861,0.00007602402,0.9947957,0.00006792772,0.00031536,0.003397906],"study_design_scores_gemma":[0.00007705078,0.001430817,0.01935287,0.00001841287,0.000110931,0.001786465,0.0000734046,0.00154831,0.9583376,0.00008160622,0.01716834,0.0000142247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759235,0.009980562,0.007190289,0.0003173314,0.0001404625,0.0001087885,0.002911137,0.0002578693,0.003170117],"genre_scores_gemma":[0.9744999,0.00368091,0.006432493,0.0001494578,0.0000933989,0.0001216473,0.009572867,0.00008445173,0.005364881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003021657,"threshold_uncertainty_score":0.01010847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1403084460132745,"score_gpt":0.4162957883799558,"score_spread":0.2759873423666813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}